NG-Circos：用于数据可视化与解读的下一代Circos
NG-Circos: next-generation Circos for data visualization and interpretation.
作者信息
Cui Ya, Cui Zhe, Xu Jianfeng, Hao Dapeng, Shi Jiejun, Wang Dan, Xiao Hui, Duan Xiaohong, Chen Runsheng, Li Wei
机构信息
Division of Computational Biomedicine, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA 92697, USA.
Division of Biostatistics, Dan L Duncan Cancer Center and Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
出版信息
NAR Genom Bioinform. 2020 Sep 3;2(3):lqaa069. doi: 10.1093/nargab/lqaa069. eCollection 2020 Sep.
Circos plots are widely used to display multi-dimensional next-generation genomic data, but existing implementations of Circos are not interactive with limited support of data types. Here, we developed next-generation Circos (NG-Circos), a flexible JavaScript-based circular genome visualization tool for designing highly interactive Circos plots using 21 functional modules with various data types. To our knowledge, NG-Circos is the most powerful software to construct interactive Circos plots. By supporting diverse data types in a dynamic browser interface, NG-Circos will accelerate the next-generation data visualization and interpretation, thus promoting the reproducible research in biomedical sciences and beyond. NG-Circos is available at https://wlcb.oit.uci.edu/NG-Circos and https://github.com/YaCui/NG-Circos.
Circos图被广泛用于展示多维下一代基因组数据，但现有的Circos实现缺乏交互性，且对数据类型的支持有限。在此，我们开发了下一代Circos（NG-Circos），这是一个基于JavaScript的灵活的环形基因组可视化工具，用于使用21个具有各种数据类型的功能模块设计高度交互式的Circos图。据我们所知，NG-Circos是构建交互式Circos图最强大的软件。通过在动态浏览器界面中支持多种数据类型，NG-Circos将加速下一代数据的可视化和解读，从而促进生物医学及其他领域的可重复研究。可通过https://wlcb.oit.uci.edu/NG-Circos和https://github.com/YaCui/NG-Circos获取NG-Circos。
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