Department of Medical Physics, Semnan University of Medical Sciences, Semnan, Iran.
Raaheaseman Center of Nuclear Medicine, Semnan University of Medical Science, Semnan, Iran.
Int J Cardiovasc Imaging. 2021 Jun;37(6):2079-2084. doi: 10.1007/s10554-021-02170-x. Epub 2021 Feb 11.
In myocardial gated SPECT imaging each cardiac cycle is divided into 8 or 16 temporal frames and the cause of the difference between 8 and 16 frames is not specified exactly. The aim of this study was to investigate the effect of myocardial detector counts and gender on the difference between 8 and 16 frames and also to compare the LVEF obtained by 8 and 16 frames with echocardiography. The study population included 84 patients who underwent gated SPECT imaging. Left ventricular parameters were assessed on 8 and 16 frames gated SPECT. LVEF was also measured with two-dimensional echocardiography within 5-10 days after gated SPECT imaging. There was a good correlation between 8 and 16 frames for calculation of LVEF (p = 0.00, r = 0.860), EDV (p = 0.00, r = 0.965) and ESV (p = 0.00, r = 0.956) in all patients. But the difference between 8 and 16 frames for calculation of LVEF (p = 0.00), EDV (p = 0.014) and ESV (p = 0.00) was statistically significant. This difference was assessed separately in females, males, patients with high photon counts and patients with low photon counts and in all subgroups was statistically significant difference in the estimation of LVEF and ESV (p < 0.05) but no significant difference in the estimation of EDV (p > 0.05). Echocardiography resulted in smaller LVEF as compared to 8 and 16 frames gated SPECT studies and there was a significant difference between the two methods (p = 0.00). The myocardial detector counts and gender have no effect on the difference between 8 and 16 frames methods and the LVEF on echocardiography is smaller than the gated SPECT, but the 8-frame is closer to echocardiography.
在心肌门控 SPECT 成像中，每个心动周期被分为 8 个或 16 个时相，并且 8 个和 16 个时相之间的差异原因没有被明确指定。本研究的目的是调查心肌探测器计数和性别对 8 个和 16 个时相之间差异的影响，并比较 8 个和 16 个时相获得的 LVEF 与超声心动图的结果。研究人群包括 84 例行门控 SPECT 成像的患者。使用 8 个和 16 个时相的门控 SPECT 评估左心室参数。在门控 SPECT 成像后 5-10 天内，使用二维超声心动图测量 LVEF。在所有患者中，8 个和 16 个时相计算 LVEF（p=0.00，r=0.860）、EDV（p=0.00，r=0.965）和 ESV（p=0.00，r=0.956）之间存在良好的相关性。但是，8 个和 16 个时相计算 LVEF（p=0.00）、EDV（p=0.014）和 ESV（p=0.00）之间的差异具有统计学意义。分别在女性、男性、高光子计数患者和低光子计数患者中以及所有亚组中，8 个和 16 个时相计算 LVEF 和 ESV 的估计值之间存在统计学显著差异（p<0.05），而 EDV 的估计值无显著差异（p>0.05）。与 8 个和 16 个时相门控 SPECT 研究相比，超声心动图导致 LVEF 较小，两种方法之间存在显著差异（p=0.00）。心肌探测器计数和性别对 8 个和 16 个时相方法之间的差异没有影响，超声心动图上的 LVEF 小于门控 SPECT，但 8 个时相更接近超声心动图。
