用[14C]2-脱氧葡萄糖法揭示的有色大鼠小脑中绒球对视动刺激的代谢反应。

Metabolic responses of the flocculus to optokinetic stimuli as revealed by the [14C]2-deoxyglucose method in pigmented rats.

作者信息

Mori K, Miyashita Y

机构信息

Department of Physiology, Faculty of Medicine, University of Tokyo, Japan.

出版信息

Neurosci Res. 1988 Feb;5(3):258-64. doi: 10.1016/0168-0102(88)90054-5.

DOI:10.1016/0168-0102(88)90054-5

PMID:3357587

Abstract

By means of the [14C]2-deoxyglucose method, metabolic activity in the flocculus during monocular temporonasal optokinetic stimulation was investigated in alert pigmented rats. Local glucose utilization rates of both flocculi were significantly enhanced in the optokinetically stimulated animals. The flocculus ipsilateral to the stimulated eye showed an enhanced local glucose utilization rate as compared with the contralateral flocculus. The most enhanced activity was localized in the middle part of the rostrocaudal extent of the ipsilateral flocculus, and was characterized by its patchy appearance in the granular layer.

摘要

通过[14C]2-脱氧葡萄糖法，在清醒的有色大鼠中研究了单眼颞鼻侧视动刺激期间绒球的代谢活性。在视动刺激的动物中，两个绒球的局部葡萄糖利用率均显著提高。与对侧绒球相比，受刺激眼同侧的绒球局部葡萄糖利用率有所提高。活性增强最明显的部位位于同侧绒球 rostrocaudal 范围的中部，其特征是在颗粒层呈斑片状。