Bailey R R, Lynn K L
Department of Nephrology, Christchurch Hospital.
N Z Med J. 1988 Apr 13;101(843):174-5.
Between January 1973 and December 1986 a total of 47 children (32 boys) under the age of 16 years had a total of 60 renal biopsies. The commonest indication for biopsy was the nephrotic syndrome, followed by macroscopic haematuria, Henoch-Schönlein nephritis and lupus nephritis. The children have been followed prospectively for a mean period of five and one-half years. One-half of the children are now in a full remission, five have reached end-stage renal failure, two have died of sepsis, two have chronic renal failure and the remainder continue to have proteinuria and/or macroscopic haematuria. Renal biopsy by an experienced operator using ultrasonic control and having the facilities of an expert histopathological service was a safe diagnostic procedure which has enabled important prognostic and therapeutic decisions to be made.
1973年1月至1986年12月期间,共有47名16岁以下儿童(32名男孩)接受了60次肾活检。活检最常见的指征是肾病综合征,其次是肉眼血尿、过敏性紫癜肾炎和狼疮性肾炎。这些儿童接受了平均五年半的前瞻性随访。现在,一半的儿童完全缓解,五名儿童已发展至终末期肾衰竭,两名儿童死于败血症,两名儿童患有慢性肾衰竭,其余儿童继续有蛋白尿和/或肉眼血尿。由经验丰富的操作人员在超声引导下进行肾活检,并具备专业组织病理学服务设施,这是一种安全的诊断程序,能够据此做出重要的预后和治疗决策。