Wolfe H M, Gross T L, Sokol R J, Bottoms S F, Thompson K L
Department of Obstetrics and Gynecology, Hutzel Hospital/Wayne State University, Detroit, Michigan.
Obstet Gynecol. 1988 May;71(5):691-6.
Studies examining the increased surgical morbidity among obese gravidas have focused mainly on differences in outcome between obese and nonobese mothers. Little is known, however, about the cause for worsened operative outcome in obese mothers or the potential impact of perioperative interventions. To define more precisely the clinical determinants of postoperative morbidity, multivariate analysis was used to relate antepartum and intrapartum variables to three measures of morbidity in 107 consecutively delivered obese women undergoing cesarean. Although obesity is clearly an operative risk factor, this study suggested that among obese gravidas, varying degrees of maternal obesity and accompanying medical complications, such as diabetes and hypertension, were not associated with greater operative morbidity. Furthermore, neither choice of skin incision nor type of anesthesia appeared to be related to operative morbidity. However, two factors potentially under the control of the clinician, increased length of surgery and operative blood loss, were associated significantly with measures of operative morbidity. A finding of worsened outcome with prophylactic antibiotics and heparin requires further study.
研究肥胖孕妇手术并发症增加的情况主要聚焦于肥胖与非肥胖母亲之间的结局差异。然而,对于肥胖母亲手术结局恶化的原因或围手术期干预的潜在影响知之甚少。为了更精确地确定术后并发症的临床决定因素,采用多变量分析将产前和产时变量与107例连续行剖宫产的肥胖妇女的三种并发症指标相关联。虽然肥胖显然是一个手术风险因素,但该研究表明,在肥胖孕妇中,不同程度的母亲肥胖以及伴随的医疗并发症,如糖尿病和高血压,与更高的手术并发症无关。此外,皮肤切口的选择和麻醉类型似乎都与手术并发症无关。然而,两个可能受临床医生控制的因素,手术时间延长和术中失血,与手术并发症指标显著相关。预防性使用抗生素和肝素导致结局恶化这一发现需要进一步研究。