Young S B, Martelly P D, Greb L, Considine G, Coustan D R
Department of Obstetrics and Gynecology, Brown University Program in Medicine, Women and Infants Hospital of Rhode Island, Providence.
Obstet Gynecol. 1988 May;71(5):736-8.
To determine whether intraumbilical oxytocin would shorten the third stage of labor, we enrolled 50 normal parturients into a randomized, double-blind protocol. Either 10 U of oxytocin diluted to 20 mL in normal saline (25 subjects) or 20 mL of normal saline alone (25 subjects) was injected into the placental circulation within one minute after cord clamping. The mean (+/- SD) duration of the third stage was 4.1 +/- 2.0 minutes in saline-treated subjects and 4.6 +/- 3.4 minutes in those treated with oxytocin. Intraumbilical oxytocin was not effective in shortening the normal third stage of labor.
为了确定脐内注射缩宫素是否会缩短第三产程，我们将50名正常产妇纳入一项随机双盲方案。在脐带夹紧后1分钟内，将10 U缩宫素用生理盐水稀释至20 mL（25名受试者）或仅20 mL生理盐水（25名受试者）注入胎盘循环。生理盐水治疗组第三产程的平均（±标准差）持续时间为4.1±2.0分钟，缩宫素治疗组为4.6±3.4分钟。脐内注射缩宫素对缩短正常第三产程无效。
