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异常子宫出血治疗决策中的差异。

Disparities in Treatment Decisions for Abnormal Uterine Bleeding.

机构信息

Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri, USA.

Saint Louis University School of Medicine, St. Louis, Missouri, USA.

出版信息

J Womens Health (Larchmt). 2021 Oct;30(10):1519-1525. doi: 10.1089/jwh.2020.8800. Epub 2021 Feb 12.

Abstract

Abnormal uterine bleeding (AUB) affects ∼1.4 million women in the United States each year. This study sought to identify differences in treatment decisions for managing noncancer-related AUB. IRB approval was obtained. This retrospective study analyzed data for all women 21-60 years old, diagnosed with AUB from July 1, 2013 through June 30, 2017, in an Obstetrics and Gynecology residents' clinic serving mostly underinsured patients. Patients with a diagnosis of postmenopausal bleeding or any gynecologic cancer were excluded. Two multivariable logistic regression models were used to identify variables independently associated with receiving surgical (vs. medical) treatment and any (vs. no) treatment. Of 2,154 patients with AUB, 1,705 women met all inclusion criteria and had complete data for analysis. In the model examining receipt of surgical (vs. medical) treatment, women ages 41-60 were 4.8 times more likely than women 21-40 years old to receive surgical treatment. Women designated as "Other" (non-White) race/ethnicity were 80.8% less likely than Black/African American patients to receive surgery. Body mass index (BMI) and insurance type were not independently associated with receiving surgical treatment. In the model examining any (vs. no) treatment, women ages 41-60 (vs. 21-40) and of unknown (vs. Black/African American) race/ethnicity were 69.6% and 50.8% less likely to receive any treatment, respectively. BMI and insurance status were not independently associated with receiving any treatment. Management of AUB differed significantly by age and race/ethnicity, but not BMI or insurance. Further investigation among larger diverse populations is warranted to test the generalizability of these findings.

摘要

异常子宫出血(AUB)影响了美国每年约 140 万名女性。本研究旨在确定非癌症相关 AUB 管理治疗决策中的差异。本研究获得了机构审查委员会的批准。这是一项回顾性研究,分析了 2013 年 7 月 1 日至 2017 年 6 月 30 日期间在一家主要为保险不足患者提供服务的妇产科住院医师诊所就诊的年龄在 21-60 岁之间、被诊断为 AUB 的所有女性的数据。排除了绝经后出血或任何妇科癌症诊断的患者。使用两种多变量逻辑回归模型来确定与接受手术(与药物治疗相比)和任何(与无治疗相比)治疗相关的独立变量。在 2154 名 AUB 患者中,1705 名女性符合所有纳入标准,并有完整数据进行分析。在接受手术(与药物治疗相比)治疗的模型中,41-60 岁的女性接受手术治疗的可能性是 21-40 岁女性的 4.8 倍。被指定为“其他”(非白人)种族/民族的女性接受手术的可能性比黑人/非裔美国患者低 80.8%。体重指数(BMI)和保险类型与接受手术治疗无关。在接受任何(与无治疗相比)治疗的模型中,41-60 岁(与 21-40 岁)和未知种族/民族(与黑人/非裔美国人)的女性接受任何治疗的可能性分别降低了 69.6%和 50.8%。BMI 和保险状况与接受任何治疗无关。AUB 的管理因年龄和种族/民族而异,但与 BMI 或保险无关。需要在更大的不同人群中进一步调查,以检验这些发现的普遍性。

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