Cancer Research UK Manchester Institute Cancer Biomarker Centre, University of Manchester, Manchester, UK; Cancer Research UK Lung Cancer Centre of Excellence, Manchester, UK.
Cancer Research UK Manchester Institute Cancer Biomarker Centre, University of Manchester, Manchester, UK; Cancer Research UK Lung Cancer Centre of Excellence, Manchester, UK.
Cancer Cell. 2021 Mar 8;39(3):297-299. doi: 10.1016/j.ccell.2021.02.002. Epub 2021 Feb 11.
In this issue of Cancer Cell, Gay et al. describe a molecular classification of small cell lung cancers and extend prior studies that highlight the potential for personalized treatments. Notably, they identify a new "inflamed" subtype that may emerge following acquired chemoresistance but which may become more susceptible to immunotherapy.
在本期《癌细胞》中，Gay 等人描述了小细胞肺癌的一种分子分类，并扩展了先前的研究，这些研究强调了个性化治疗的潜力。值得注意的是，他们发现了一种新的“炎症”亚型，这种亚型可能在获得性化疗耐药后出现，但可能对免疫疗法更敏感。
