Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8577, Japan.
Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8577, Japan.
BMC Womens Health. 2021 Feb 12;21(1):64. doi: 10.1186/s12905-021-01207-6.
The method of communicating a positive cancer screening result should seek to alleviate psychological distress associated with a positive result. We evaluated whether the provision of information through a leaflet would help reduce psychological distress in a randomized controlled trial.
The participants were women aged 20-69 years who were about to undergo cervical cancer screening at health centers. Before the screening, they received hypothetical screening results, with a leaflet (intervention group, n = 493) or without it (control group, n = 479), randomly. Their psychological distress and intention to undergo further examination were then compared between the intervention and control groups.
After the intervention (providing a leaflet with hypothetical screening results), psychological distress appeared to be higher in the control group than in the intervention group among those who received a hypothetical positive screening result (odds ratio: 2.57, 95% confidence interval: 1.87-3.54), while 95% and 97% of those in the intervention and control groups, respectively, reported that they would undergo further examination.
Information provision might help reduce psychological distress but not hinder further examination among women who screen positive for cervical cancer.
UMIN Clinical Trials Registry UMIN000029894. Date of Registration: November 2017.
传递阳性癌症筛查结果的方法应寻求减轻与阳性结果相关的心理困扰。我们通过一项随机对照试验评估了通过发放宣传册提供信息是否有助于减少心理困扰。
参与者为年龄在 20-69 岁之间的女性，她们将在卫生中心接受宫颈癌筛查。在筛查前，她们收到了假设的筛查结果，并随机分为接受（干预组，n=493）或不接受（对照组，n=479）宣传册。然后比较干预组和对照组之间的心理困扰和进一步检查的意愿。
在干预（提供假设筛查结果的宣传册）后，对于收到假设阳性筛查结果的女性，对照组的心理困扰似乎高于干预组（比值比：2.57，95%置信区间：1.87-3.54），而干预组和对照组分别有 95%和 97%的女性表示将进行进一步检查。
对于宫颈癌筛查阳性的女性，信息提供可能有助于减轻心理困扰，但不会阻碍进一步检查。
UMIN 临床研究注册 UMIN000029894。注册日期：2017 年 11 月。
