Calin Mariana, Vishnu Jithin, Thirathipviwat Pramote, Popa Monica-Mihaela, Krautz Maria, Manivasagam Geetha, Gebert Annett
Institute for Complex Materials, Leibniz Institute for Solid State and Materials Research, Dresden (IFW Dresden), Helmholtzstr-20, D-01069 Dresden, Germany.
Centre for Biomaterials Cellular and Molecular Theranostics, CBCMT, Vellore Institute of Technology, Vellore, India.
Mater Sci Eng C Mater Biol Appl. 2021 Feb;121:111733. doi: 10.1016/j.msec.2020.111733. Epub 2020 Nov 14.
Present work unveils novel magnetic resonance imaging (MRI) compatible glassy Ti-Zr-Nb-Hf-Si alloys designed based on a high entropy alloys approach, by exploring the central region of multi-component alloy phase space. Phase analysis has revealed the amorphous structure of developed alloys, with a higher thermal stability than the conventional metallic glasses. The alloys exhibit excellent corrosion properties in simulated body fluid. Most importantly, the weak paramagnetic nature (ultralow magnetic susceptibility) and superior radiopacity (high X-ray attenuation coefficients) offer compatibility with medical diagnostic imaging systems thereby opening unexplored realms for biomedical applications.
目前的工作揭示了基于高熵合金方法设计的新型磁共振成像（MRI）兼容玻璃态Ti-Zr-Nb-Hf-Si合金，通过探索多组分合金相空间的中心区域。相分析表明所开发合金具有非晶结构，其热稳定性高于传统金属玻璃。这些合金在模拟体液中表现出优异的腐蚀性能。最重要的是，其弱顺磁性质（超低磁化率）和卓越的射线不透性（高X射线衰减系数）使其与医学诊断成像系统兼容，从而为生物医学应用开辟了未被探索的领域。
