Department of Surgery, Transplantation Division, University of Minnesota, Minneapolis, MN, USA.
Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.
Nat Rev Nephrol. 2021 Aug;17(8):509-510. doi: 10.1038/s41581-021-00407-5. Epub 2021 Feb 12.
Living donor kidney transplantation benefits the recipient. However, kidney failure can occur in a small fraction of donors — the risk is not uniform but varies according to donor characteristics. Studies to date have failed to match on important factors, such as era, environment or family history. Long-term studies with well-matched healthy controls are therefore needed.
活体供肾移植使受者受益。然而，一小部分供者会发生肾衰竭——这种风险并非一致，而是因供者特征而异。迄今为止的研究未能匹配重要因素，如时代、环境或家族史。因此，需要进行长期的、有良好匹配的健康对照研究。
