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因恶化的心力衰竭症状而延迟就医:预测因素及与心脏事件的关联。

Delay in seeking medical care for worsening heart failure symptoms: predictors and association with cardiac events.

机构信息

College of Nursing, University of Kentucky, 751 Rose Street, Lexington, KY 40536, USA.

School of Nursing, University of Louisville, 555 S Floyd Street, Louisville, KY 40202, USA.

出版信息

Eur J Cardiovasc Nurs. 2021 Jun 29;20(5):454-463. doi: 10.1093/eurjcn/zvaa032.

Abstract

AIMS

The association of delay in seeking medical care to subsequent cardiac events remains unknown in patients with worsening heart failure (HF) symptoms. The aims of this study were to (i) identify factors predicting care-seeking delay and (ii) examine the impact of care-seeking delay on subsequent cardiac rehospitalization or death.

METHODS AND RESULTS

We studied 153 patients hospitalized with an exacerbation of HF. Potential predictors of delay including demographic, clinical, psychosocial, cognitive, and behavioural variables were collected. Patients were followed for 3 months after discharge to determine time to the first cardiac rehospitalization or death. The median delay time was 134 h (25th and 75th percentiles 49 and 364 h). Non-linear regression showed that New York Heart Association functional class III/IV (P = 0.001), worse depressive symptoms (P = 0.004), better HF knowledge (P = 0.003), and lower perceived somatic awareness (P = 0.033) were predictors of delay time from patient perception of worsening HF to subsequent hospital admission. Cox regression revealed that patients who delayed longer (more than 134 h) had a 1.93-fold higher risk of experiencing cardiac events (P = 0.044) compared to non-delayers.

CONCLUSIONS

Care-seeking delay in patients with worsening HF symptoms was significantly associated with an increased risk of rehospitalization and mortality after discharge. Intervention strategies addressing functional status, psychological state, cognitive and behavioural factors are essential to reduce delay and thereby improve outcomes.

摘要

目的

在心力衰竭(HF)症状恶化的患者中,寻求医疗护理的延迟与随后的心脏事件的关联尚不清楚。本研究的目的是:(i)确定预测寻求护理延迟的因素;(ii)检查寻求护理延迟对随后的心脏再入院或死亡的影响。

方法和结果

我们研究了 153 例因 HF 恶化而住院的患者。收集了潜在的预测延迟因素,包括人口统计学、临床、心理社会、认知和行为变量。患者在出院后随访 3 个月,以确定首次心脏再入院或死亡的时间。中位延迟时间为 134 小时(25 百分位数和 75 百分位数分别为 49 小时和 364 小时)。非线性回归显示,纽约心脏协会功能分类 III/IV(P=0.001)、更严重的抑郁症状(P=0.004)、更好的 HF 知识(P=0.003)和较低的躯体感知(P=0.033)是从患者对 HF 恶化的感知到随后住院的延迟时间的预测因素。Cox 回归显示,与非延迟者相比,延迟时间较长(超过 134 小时)的患者发生心脏事件的风险增加 1.93 倍(P=0.044)。

结论

HF 症状恶化患者的寻求护理延迟与出院后再入院和死亡率增加显著相关。解决功能状态、心理状态、认知和行为因素的干预策略对于减少延迟从而改善预后至关重要。

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