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立体定向齿状核切开术治疗痉挛及其他疾病的长期评估

Long-term assessment of stereotactic dentatotomy for spasticity and other disorders.

作者信息

Siegfried J, Verdie J C

出版信息

Acta Neurochir (Wien). 1977(Suppl 24):41-8. doi: 10.1007/978-3-7091-8482-0_6.

Abstract

In the 60's stereotactic electrocoagulation of the dentate nucleus became a promising approach in the neurosurgical treatment of muscular hypertonicity, particularly when spasticity was evident. A relatively satisfactory improvement of spasticity has been reported earlier as a result and the authors were supporting these clinical results in previous publications. A long-term assessment of the results obtained in a large series of patients would permit a better evaluation of the effect of the operation. Analysing 109 stereotactic electrocoagulations of the dentate nucleus on 50 patients mainly in cases of cerebral palsy over a period of more than 10 years (most patients underwent a bilateral dentatotomy), the authors give a more realistic appreciation of the results, which depend on the criteria chosen. In 30% of the cases a clear improvement in the spasticity was obtained, and in 50% of all cases, nursing and rehabilitation were facilitated. The stereotactic dentatotomy never completely cured the spasticity and spectacular results were never observed, but the operation can be performed without complications and an unexpected neurological deficit did not occur. The role of the stereotactic dentatotomy and other neurosurgical methods in the treatment of spasticity has to be evaluated more critically.

摘要

在20世纪60年代,齿状核的立体定向电凝术成为神经外科治疗肌肉张力亢进的一种有前景的方法,尤其是在痉挛明显时。此前已有报道称痉挛得到了相对令人满意的改善,作者在之前的出版物中也支持这些临床结果。对大量患者的长期评估结果将有助于更好地评估手术效果。作者分析了10多年来对50例主要为脑瘫患者进行的109次齿状核立体定向电凝术(大多数患者接受了双侧齿状核切开术),根据所选标准对结果给出了更实际的评价。30%的病例痉挛明显改善,50%的病例护理和康复得到便利。立体定向齿状核切开术从未完全治愈痉挛,也从未观察到显著效果,但该手术可无并发症地进行,且未出现意外的神经功能缺损。必须更严格地评估立体定向齿状核切开术和其他神经外科方法在治疗痉挛中的作用。

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