Benhamou C L, Brigant S, Tourlière D, Carter H, Bardet M, Caplan F, Luthier F
Service de Rhumatologie, Hôpital de la Source, Orléans.
Rev Rhum Mal Osteoartic. 1988 Feb;55(2):99-105.
Suspecting the presence of a myeloma focus in a forest area of the Loiret department, we have undertaken a retrospective epidemiological survey on this disease. Three surveys were conducted, between 1972 and 1982: the first one among general practitioners; the second one was carried out from immuno-electrophoreses performed at the University Hospital in Orleans; the third survey was carried out from reports on the medical causes of deaths. The mean number of myelomas in the Loiret (0.029 p. cent) is comparable to the national mean (0.025 p. cent), with a sex ratio of 47.09 p. cent of men, also quite similar to the national sex ratio (46.7 p. cent). The different districts were classified according to the percentages observed in "neutral areas" (mean plus or minus a typical variation), "cold areas" (between one and two typical variations below the mean) and "hot areas" (between one and two typical variations above the mean). These results do not permit to ascertain the existence of a geographical focus of myelomas in Loiret but require a more in-depth study of "hot areas".
怀疑卢瓦雷省某林区存在骨髓瘤病灶，我们针对这种疾病开展了一项回顾性流行病学调查。在1972年至1982年间进行了三项调查：第一项是针对全科医生；第二项是根据奥尔良大学医院进行的免疫电泳结果开展；第三项调查是根据死亡医学原因报告进行。卢瓦雷省骨髓瘤的平均数量（0.029%）与全国平均水平（0.025%）相当，男性比例为47.09%，也与全国性别比例（46.7%）非常相似。根据在“中性区域”（均值加减一个典型变异）、“寒冷区域”（低于均值一至两个典型变异）和“炎热区域”（高于均值一至两个典型变异）观察到的百分比对不同地区进行了分类。这些结果无法确定卢瓦雷省存在骨髓瘤的地理病灶，但需要对“炎热区域”进行更深入的研究。
