Department of Obstetrics and Gynecology, Hôpital Foch, Université de Paris Ouest (UVSQ), Paris, France.
Department of Obstetrics and Gynecology, Hôpital Foch, Université de Paris Ouest (UVSQ), Paris, France.
Fertil Steril. 2021 Mar;115(3):531-532. doi: 10.1016/j.fertnstert.2020.12.004. Epub 2021 Feb 10.
Recurrent pregnancy loss (RPL), defined as two to three spontaneous pregnancy terminations occurring before 12 weeks of gestation, affects approximately 1% of the general population. The causes may include congenital factors that originate with the quality of the gametes (sperm or oocyte) or the resulting embryo, or factors that originate within the uterus. Alterations of endometrial receptivity from endometriosis and/or endometritis, which are associated with impaired action of progesterone, have also been implicated in RPL. Finally, immunologic factors and thrombophilia, congenital and acquired, have also been suspected to cause RPL.
复发性流产（RPL）定义为发生在妊娠 12 周之前的两次至三次自然妊娠终止，影响约 1%的普通人群。其病因可能包括源于配子（精子或卵子）或由此产生的胚胎质量的先天性因素，或源于子宫内的因素。子宫内膜容受性的改变，如子宫内膜异位症和/或子宫内膜炎，与孕激素作用受损有关，也与 RPL 有关。最后，免疫因素和先天性及获得性的血栓形成倾向也被怀疑导致 RPL。
