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髋部骨折手术后 30 天患者的死亡率:两种预测模型中 Charlson 合并症指数评分和 ASA 评分的比较。

30-day mortality in patients after hip fracture surgery: A comparison of the Charlson Comorbidity Index score and ASA score used in two prediction models.

机构信息

Orthopaedic Department, Orthopaedic Research Centre, St.Olavs Hospital, Trondheim University Hospital, Postboks 3250 Torgarden, 7006, Trondheim, Norway; Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, NTNU, Faculty of Medicine and Health Sciences, N-7491 Trondheim, Norway.

Orthopaedic Department, Orthopaedic Research Centre, St.Olavs Hospital, Trondheim University Hospital, Postboks 3250 Torgarden, 7006, Trondheim, Norway.

出版信息

Injury. 2021 Aug;52(8):2379-2383. doi: 10.1016/j.injury.2021.02.004. Epub 2021 Feb 4.

Abstract

OBJECTIVE

To compare the Charlson Comorbidity Index (CCI) and American Society of Anesthesiologists (ASA) Physical Status Classification used in two prediction models for 30-day mortality after hip fracture surgery.

STUDY DESIGN AND SETTING

Data from 3651 patients (mean age: 83 years) from a Norwegian University Hospital were retrospectively obtained and randomly divided into two cohorts: a model cohort (n = 1825) to develop two prediction models with CCI and ASA as the main predictors, and a validation cohort (n = 1826) to assess the predictive ability of both models. A receiver operating characteristic (ROC) curve determined the best model to predict mortality.

RESULTS

Area under the ROC curve at 30 days was 0.726 (p = 0.988) for both the CCI- and ASA-model. The chosen cut-off-points on the ROC curve for CCI- and ASA-model corresponded to similar model sensitivities of 0.657 and specificities of 0.680 and 0.679, respectively. Hence, each model predicts correctly 66% (n = 96) of the mortalities and 68% (n = 1132 and n = 1131) of the survivals. 23% (n = 33) of the mortalities were predicted by neither model.

CONCLUSION

The CCI- and ASA-model had equal predictive ability of 30-day mortality after hip fracture. Considering the effort involved in calculating Charlson Comorbidity Index score, the ASA score may be the preferred tool to predict the 30-day mortality after hip fracture.

摘要

目的

比较 Charlson 合并症指数(CCI)和美国麻醉医师协会(ASA)身体状况分类在两种预测模型中用于髋部骨折手术后 30 天死亡率的效果。

研究设计和设置

回顾性地从挪威一家大学医院获得了 3651 名患者(平均年龄:83 岁)的数据,并将其随机分为两个队列:模型队列(n=1825)用于开发以 CCI 和 ASA 为主要预测因子的两种预测模型,验证队列(n=1826)用于评估两种模型的预测能力。接收者操作特征(ROC)曲线确定了预测死亡率的最佳模型。

结果

30 天 ROC 曲线下面积为 CCI 模型和 ASA 模型的 0.726(p=0.988)。ROC 曲线上选择的 CCI 模型和 ASA 模型的截断点对应于相似的模型灵敏度,分别为 0.657 和 0.680、0.679。因此,每个模型正确预测了 66%(n=96)的死亡率和 68%(n=1132 和 n=1131)的存活率。两种模型都未能预测到 23%(n=33)的死亡。

结论

CCI 模型和 ASA 模型对髋部骨折后 30 天死亡率的预测能力相等。考虑到计算 Charlson 合并症指数评分所涉及的工作量,ASA 评分可能是预测髋部骨折后 30 天死亡率的首选工具。

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