Orthopaedic Department, Orthopaedic Research Centre, St.Olavs Hospital, Trondheim University Hospital, Postboks 3250 Torgarden, 7006, Trondheim, Norway; Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, NTNU, Faculty of Medicine and Health Sciences, N-7491 Trondheim, Norway.
Orthopaedic Department, Orthopaedic Research Centre, St.Olavs Hospital, Trondheim University Hospital, Postboks 3250 Torgarden, 7006, Trondheim, Norway.
Injury. 2021 Aug;52(8):2379-2383. doi: 10.1016/j.injury.2021.02.004. Epub 2021 Feb 4.
To compare the Charlson Comorbidity Index (CCI) and American Society of Anesthesiologists (ASA) Physical Status Classification used in two prediction models for 30-day mortality after hip fracture surgery.
Data from 3651 patients (mean age: 83 years) from a Norwegian University Hospital were retrospectively obtained and randomly divided into two cohorts: a model cohort (n = 1825) to develop two prediction models with CCI and ASA as the main predictors, and a validation cohort (n = 1826) to assess the predictive ability of both models. A receiver operating characteristic (ROC) curve determined the best model to predict mortality.
Area under the ROC curve at 30 days was 0.726 (p = 0.988) for both the CCI- and ASA-model. The chosen cut-off-points on the ROC curve for CCI- and ASA-model corresponded to similar model sensitivities of 0.657 and specificities of 0.680 and 0.679, respectively. Hence, each model predicts correctly 66% (n = 96) of the mortalities and 68% (n = 1132 and n = 1131) of the survivals. 23% (n = 33) of the mortalities were predicted by neither model.
The CCI- and ASA-model had equal predictive ability of 30-day mortality after hip fracture. Considering the effort involved in calculating Charlson Comorbidity Index score, the ASA score may be the preferred tool to predict the 30-day mortality after hip fracture.
比较 Charlson 合并症指数(CCI)和美国麻醉医师协会(ASA)身体状况分类在两种预测模型中用于髋部骨折手术后 30 天死亡率的效果。
回顾性地从挪威一家大学医院获得了 3651 名患者(平均年龄:83 岁)的数据,并将其随机分为两个队列:模型队列(n=1825)用于开发以 CCI 和 ASA 为主要预测因子的两种预测模型,验证队列(n=1826)用于评估两种模型的预测能力。接收者操作特征(ROC)曲线确定了预测死亡率的最佳模型。
30 天 ROC 曲线下面积为 CCI 模型和 ASA 模型的 0.726(p=0.988)。ROC 曲线上选择的 CCI 模型和 ASA 模型的截断点对应于相似的模型灵敏度,分别为 0.657 和 0.680、0.679。因此,每个模型正确预测了 66%(n=96)的死亡率和 68%(n=1132 和 n=1131)的存活率。两种模型都未能预测到 23%(n=33)的死亡。
CCI 模型和 ASA 模型对髋部骨折后 30 天死亡率的预测能力相等。考虑到计算 Charlson 合并症指数评分所涉及的工作量,ASA 评分可能是预测髋部骨折后 30 天死亡率的首选工具。