Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, USA.
Oper Neurosurg (Hagerstown). 2021 May 13;20(6):E442-E443. doi: 10.1093/ons/opab020.
Spasticity is a common debilitating condition after central nervous system injury. The principal therapies-sedating antispasticity medications and focal therapies (eg, botulinum toxin)-may not provide sufficient reduction in tone, have intolerable side effects, and lose efficacy over time. Selective neurectomy is a surgical option for durable reduction in tone.1-6 Although commonly performed internationally, neurectomies are used less often within the USA. We present the surgical case of a 23-yr-old woman with cerebral palsy and severe spastic diplegia. Medications, injections, and tendon surgeries had failed to relieve her spastic lower extremities. She presented with crouch gait, adductor scissoring, and bilateral equinovarus. She had previously benefitted significantly from bilateral hamstring and obturator neurectomies, with improvement in mobility. She desired tibial neurectomies for her bilateral equinovarus, which impacted her gait substantially. To reduce unwanted plantarflexion and internal rotation tone, selective neurectomies of the motor nerves to the medial and lateral gastrocnemius, soleus, and posterior tibialis muscles were performed. The surgical video details a technique for longitudinally opening the epineurium, separating small nerves into their individual fascicles, and subdividing submillimeter fascicles by approximately 50% to 60% of the fascicle cross-sectional area. She reported significant improvement in gait, her modified Ashworth score dropped from 3 to 0, and her motor power remained unchanged, which is equivalent or better than most published results.2,7 Neurectomies are a highly effective procedure for focal extremity spasticity. Additional clinical series or trials would help establish the appropriate indications and durability and quantify the risks and benefits. The patient consented to treatment and publication.
痉挛是中枢神经系统损伤后的一种常见致残情况。主要的治疗方法——镇静抗痉挛药物和局部治疗(例如,肉毒毒素)——可能无法充分降低肌张力,会产生无法忍受的副作用,并且随着时间的推移疗效会降低。选择性神经切除术是一种持久降低肌张力的手术选择。1-6 尽管在国际上普遍实施,但在美国,神经切除术的应用较少。我们介绍了一位 23 岁女性的手术案例,她患有脑瘫和严重的痉挛性双瘫。药物、注射和肌腱手术都未能缓解她的痉挛性下肢。她表现为蹲伏步态、内收剪刀步态和双侧马蹄内翻。她之前从双侧腘绳肌和闭孔神经切除术受益显著,移动能力得到改善。她希望对双侧马蹄内翻进行胫骨神经切除术,这对她的步态有很大影响。为了降低不必要的跖屈和内旋肌张力,对内侧和外侧腓肠肌、比目鱼肌和胫骨后肌的运动神经进行了选择性神经切除术。手术视频详细介绍了一种技术,用于纵向切开神经外膜,将小神经分离成各自的束,然后将亚毫米束细分约 50%至 60%的束横截面积。她报告说步态有了显著改善,改良的 Ashworth 评分从 3 分降至 0 分,运动能力保持不变,这与大多数已发表的结果相当或更好。2,7 神经切除术是治疗局灶性肢体痉挛的一种非常有效的方法。更多的临床系列或试验将有助于确定适当的适应证和持久性,并量化风险和益处。患者同意接受治疗和发表。