Arab Academy for Science and Technology, Egypt.
Health Informatics J. 2021 Jan-Mar;27(1):1460458221991882. doi: 10.1177/1460458221991882.
Autism Spectrum Disorder (Autism) is a developmental disorder that impedes the social and communication capabilities of a person through out his life. Early detection of autism is critical in contributing to better prognosis. In this study, the use of home videos to provide accessible diagnosis is investigated. A machine learning approach is adopted to detect autism from home videos. Feature selection and state-of-the-art classification methods are applied to provide a sound diagnosis based on home video ratings obtained from non-clinicians feedback. Our models results indicate that home videos can effectively detect autistic group with True Positive Rate reaching 94.05% using Support Vector Machines and backwards feature selection. In this study, human-interpretable models are presented to elucidate the reasoning behind the classification process and its subsequent decision. In addition, the prime features that need to be monitored for early autism detection are revealed.
自闭症谱系障碍(自闭症)是一种发育障碍,它会阻碍一个人一生的社交和沟通能力。早期发现自闭症对于改善预后至关重要。在这项研究中,我们研究了使用家庭视频进行可及性诊断。我们采用机器学习方法从家庭视频中检测自闭症。应用特征选择和最先进的分类方法,根据非临床医生反馈的家庭视频评分提供可靠的诊断。我们的模型结果表明,使用支持向量机和反向特征选择,家庭视频可以有效地检测自闭症群体,真阳性率达到 94.05%。在这项研究中,我们提出了可解释的模型,以阐明分类过程及其后续决策的推理。此外,还揭示了需要监测的主要特征,以进行早期自闭症检测。