对比增强 T1 加权 Dixon 水脂成像评估早期类风湿关节炎患者手部的骨髓炎和侵蚀病变，根据 RAMRIS 标准。
Contrast-enhanced T1-weighted Dixon water- and fat-only images to assess osteitis and erosions according to RAMRIS in hands of patients with early rheumatoid arthritis.
机构信息
Department of Medical Imaging - Musculoskeletal Imaging Unit - Cliniques Universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique (IREC), Avenue Hippocrate 10, 1200 Brussels, Belgium.
Department of Rheumatology - Cliniques Universitaires Saint-Luc - Université Catholique de Louvain - Institut de Recherche Expérimentale et Clinique (IREC), Avenue Hippocrate 10, 1200 Brussels, Belgium.
出版信息
Diagn Interv Imaging. 2021 Jul-Aug;102(7-8):439-445. doi: 10.1016/j.diii.2021.01.011. Epub 2021 Feb 11.
PURPOSE
To assess the agreement between readers using contrast-enhanced T1-weighted Dixon water- and fat-only images and OMERACT-recommended sequences for the scoring of osteitis and erosions according to the rheumatoid arthritis (RA) MRI scoring system (RAMRIS) in hands of patients with early RA.
MATERIALS AND METHODS
Both hands of 24 patients (16 women, 8 men; mean age, 45.7±14.5 [SD] years; age range: 25-70 years) with early RA were prospectively imaged with fat-saturated T2-weighted sequences, non-Dixon T1-weighted imaging prior to contrast material injection and T1-weighted Dixon imaging after contrast material injection at 1.5T. There were Two radiologists separately quantified osteitis and erosions according to RAMRIS using contrast-enhanced T1-weighted Dixon water-only and fat-saturated T2-weighted images for osteitis and contrast-enhanced T1-weighted Dixon fat-only and T1-weighted images prior to contrast material injection for erosions. Intraclass correlation coefficients (ICC) were calculated to assess inter-technique, intra-observer and inter-observer agreement.
RESULTS
Mean ICC for the agreement between Dixon and non-Dixon images ranged from 0.68 (95%CI: 0.20-0.90) to 0.99 (95%CI: 0.95-1.00) for the scoring of osteitis and from 0.77 (95%CI: 0.38-0.93) to 0.99 (95%CI: 0.95-1.00) for the scoring of erosions. Mean ICC for the agreement between first and second readings ranged from 0.94 (95%CI: 0.81-0.98) to 0.97 (95%CI: 0.91-0.99) for the scoring of osteitis using Dixon and 0.91 (95%CI: 0.72-0.97) to 0.98 (95%CI: 0.92-0.99) using non-Dixon images and from 0.80 (95%CI: 0.45-0.94) to 0.97 (95%CI: 0.91-0.99) for the scoring of erosions using Dixon and 0.72 (95%CI: 0.29-0.91) to 0.98 (95%CI: 0.92-0.99) using non-Dixon images.
CONCLUSION
Contrast-enhanced T1-weighted Dixon water- and fat-only images can serve as an alternative to fat-saturated T2-weighted and T1-weighted MRI sequences for the assessment of osteitis and erosions according to the RAMRIS scoring system in hands of patients with early RA.
目的
评估使用对比增强 T1 加权 Dixon 水和脂肪仅图像和 OMERACT 推荐的序列与根据 RAMRIS 评分系统对早期 RA 患者手部的骨炎和侵蚀进行评分的读者之间的一致性。
材料和方法
前瞻性地对 24 例（16 名女性，8 名男性；平均年龄 45.7±14.5[SD]岁；年龄范围：25-70 岁）早期 RA 患者的双手进行脂肪饱和 T2 加权序列、对比前非 Dixon T1 加权成像和对比后 1.5T 造影剂注射后的 Dixon T1 加权成像。两名放射科医生分别使用对比增强 T1 加权 Dixon 水和脂肪仅图像以及对比增强 T1 加权 Dixon 脂肪仅和造影前 T1 加权图像根据 RAMRIS 对骨炎和侵蚀进行评分。计算了组内相关系数（ICC）来评估技术间、观察者内和观察者间的一致性。
结果
对于骨炎评分，Dixon 和非 Dixon 图像之间的平均 ICC 范围为 0.68（95%CI：0.20-0.90）至 0.99（95%CI：0.95-1.00），对于侵蚀评分，Dixon 和非 Dixon 图像之间的平均 ICC 范围为 0.77（95%CI：0.38-0.93）至 0.99（95%CI：0.95-1.00）。使用 Dixon 进行骨炎评分时，第一和第二读数之间的平均 ICC 范围为 0.94（95%CI：0.81-0.98）至 0.97（95%CI：0.91-0.99），使用非 Dixon 图像时，平均 ICC 范围为 0.91（95%CI：0.72-0.97）至 0.98（95%CI：0.92-0.99）。使用 Dixon 进行侵蚀评分时，第一和第二读数之间的平均 ICC 范围为 0.80（95%CI：0.45-0.94）至 0.97（95%CI：0.91-0.99），使用非 Dixon 图像时，平均 ICC 范围为 0.72（95%CI：0.29-0.91）至 0.98（95%CI：0.92-0.99）。
结论
对比增强 T1 加权 Dixon 水和脂肪仅图像可作为脂肪饱和 T2 加权和 T1 加权 MRI 序列的替代方法，用于根据 RAMRIS 评分系统评估早期 RA 患者手部的骨炎和侵蚀。
Zotero 插件