Department of Oral and Maxillofacial Surgery, Yokohama Minami Mutual Hospital.
Department of Oral Medicine, Oral and Maxillofacial Surgery, Tokyo Dental College.
Bull Tokyo Dent Coll. 2021 Mar 13;62(1):41-47. doi: 10.2209/tdcpublication.2020-0002. Epub 2021 Feb 15.
Many cases of immunoglobulin G4-related disease (IgG4-RD) involve swelling of the salivary glands, often affecting the parotid and submandibular glands in the head and neck region, in addition to the lacrimal glands. Cases of IgG4-RD characterized by swelling of the palatal glands, however, are extremely rare. Here, we describe a case of IgG4-RD involving bilateral swelling of the palatal glands. An 83-year-old man presented at our hospital with bilateral swelling of the lacrimal and submandibular glands. A solid bilateral swelling of normal colour and unclear boundaries was observed in the hard palate. The lesion was diagnosed as IgG4-RD and steroid therapy initiated. A subsequent decrease in swelling of the palatal, lacrimal, and submandibular glands was confirmed by magnetic resonance imaging. These results indicate that dentists should suspect IgG4-RD in patients presenting with bilateral swelling of the palatal glands.
许多免疫球蛋白 G4 相关疾病（IgG4-RD）的病例涉及唾液腺肿胀，通常影响头颈部的腮腺和颌下腺，此外还影响泪腺。然而，以腭腺肿胀为特征的 IgG4-RD 病例极为罕见。在这里，我们描述了一例涉及双侧腭腺肿胀的 IgG4-RD 病例。一名 83 岁男性因双侧泪腺和颌下腺肿胀而到我院就诊。硬腭上观察到双侧肿胀呈实性，颜色正常，边界不清。病变被诊断为 IgG4-RD，并开始进行类固醇治疗。通过磁共振成像确认了腭、泪腺和颌下腺肿胀的随后减少。这些结果表明，牙医在遇到双侧腭腺肿胀的患者时应怀疑 IgG4-RD。
