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本文引用的文献

1
Long-term therapeutic effects of dextrose prolotherapy in patients with hypermobility of the temporomandibular joint: a single-arm study with 1-4 years' follow up.葡萄糖注射疗法对颞下颌关节活动度过大患者的长期治疗效果:一项随访1至4年的单臂研究
Br J Oral Maxillofac Surg. 2017 Jun;55(5):465-470. doi: 10.1016/j.bjoms.2016.12.002. Epub 2017 Apr 29.
2
Single Injection Technique Prolotherapy for Hypermobility Disorders of TMJ Using 25 % Dextrose: A Clinical Study.使用25%葡萄糖的单注射技术注射疗法治疗颞下颌关节活动度过大疾病的临床研究
J Maxillofac Oral Surg. 2017 Jun;16(2):226-230. doi: 10.1007/s12663-016-0944-0. Epub 2016 Jul 25.
3
A Systematic Review of Dextrose Prolotherapy for Chronic Musculoskeletal Pain.葡萄糖注射疗法治疗慢性肌肉骨骼疼痛的系统评价
Clin Med Insights Arthritis Musculoskelet Disord. 2016 Jul 7;9:139-59. doi: 10.4137/CMAMD.S39160. eCollection 2016.
4
Modified dextrose prolotherapy for recurrent temporomandibular joint dislocation.改良葡萄糖注射疗法治疗复发性颞下颌关节脱位
Br J Oral Maxillofac Surg. 2014 Jan;52(1):63-6. doi: 10.1016/j.bjoms.2013.08.018. Epub 2013 Sep 21.
5
Prolotherapy: a clinical review of its role in treating chronic musculoskeletal pain.增生疗法:治疗慢性肌肉骨骼疼痛的临床综述。
PM R. 2011 Jun;3(6 Suppl 1):S78-81. doi: 10.1016/j.pmrj.2011.04.003.
6
A randomized double-blind trial of dextrose-glycerine-phenol injections for chronic, low back pain.葡萄糖-甘油-苯酚注射液治疗慢性腰痛的随机双盲试验
J Spinal Disord. 1993 Feb;6(1):23-33.

注射疗法治疗颞下颌关节紊乱症的疗效:一项探索性研究。

Efficacy of Prolotherapy in Temporomandibular Joint Disorders: An Exploratory Study.

作者信息

Dasukil Saubhik, Shetty Sujeeth Kumar, Arora Geetanjali, Degala Saikrishna

机构信息

Department of Oral and Maxillofacial Surgery, JSS Dental College and Hospital, Mysore, India.

出版信息

J Maxillofac Oral Surg. 2021 Mar;20(1):115-120. doi: 10.1007/s12663-020-01328-9. Epub 2020 Jan 13.

DOI:10.1007/s12663-020-01328-9
PMID:33584052
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7855124/
Abstract

INTRODUCTION

Temporomandibular joint (TMJ) disorders can be treated by both conservative and surgical approaches. Conservative interventions with predictable benefits can be considered as first-line treatment for such disorders. Dextrose prolotherapy is one of the most promising approaches in the management of TMDs, especially in refractory cases where other conservative management has failed.

AIM

To study the efficacy of prolotherapy and to establish it as an effective procedure in patients with TMJ disorders, to provide long-term solution to chronic TMJ pain and dysfunctions.

PATIENTS AND METHODS

We conducted a study on 25 patients suffering from various TMJ disorders who were treated with prolotherapy, the solution consisting of 1 part of 50% dextrose (0.75 ml); 2 parts of lidocaine (1.5 ml); and 1 part of warm saline (0.75 ml). The standard programme is to repeat the injections three times, at 2-week interval, which totals four injection appointments over 6 weeks with 3-month follow-up.

RESULTS

There was appreciable reduction in tenderness in TMJ and masticatory muscles with significant improvement in mouth opening. The effect of the treatment in improving clicking and deviation of TMJ was found to be statistically significant ( < 0.05). There were no permanent complications.

CONCLUSION

Our study concluded that prolotherapy is an effective therapeutic modality that reduces TMJ pain, improves joint stability and range of motion in a majority of patients. It can be a first-line treatment option as it is safe, economical and an easy procedure associated with minimal morbidity.

摘要

引言

颞下颌关节(TMJ)疾病可通过保守和手术方法进行治疗。具有可预测疗效的保守干预措施可被视为这类疾病的一线治疗方法。葡萄糖注射疗法是颞下颌关节紊乱病管理中最有前景的方法之一,尤其是在其他保守治疗失败的难治性病例中。

目的

研究注射疗法的疗效,并将其确立为治疗颞下颌关节疾病患者的有效方法,为慢性颞下颌关节疼痛和功能障碍提供长期解决方案。

患者与方法

我们对25例患有各种颞下颌关节疾病的患者进行了一项研究,这些患者接受了注射疗法治疗,所用溶液由1份50%葡萄糖(0.75毫升)、2份利多卡因(1.5毫升)和1份温生理盐水(0.75毫升)组成。标准方案是每隔2周重复注射3次,在6周内共进行4次注射预约,并进行3个月的随访。

结果

颞下颌关节和咀嚼肌压痛明显减轻,开口度显著改善。发现该治疗对改善颞下颌关节弹响和偏斜的效果具有统计学意义(<0.05)。没有永久性并发症。

结论

我们的研究得出结论,注射疗法是一种有效的治疗方式,可减轻大多数患者的颞下颌关节疼痛,改善关节稳定性和活动范围。它可以作为一线治疗选择,因为它安全、经济且操作简单,发病率极低。