Gibaly Amr, Abdelmoiz Mohamed, Alghandour Ahmed Nagi
Department of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, Beni-Suef University, East Nile educational compound, Beni-Suef, 62764, Egypt.
Clin Oral Investig. 2024 Aug 8;28(9):475. doi: 10.1007/s00784-024-05830-z.
to compare the combined effect of Prolotherapy and Deep Dry Needling (DDN) versus DDN effect on relieving the symptoms of Temporomandibular joint (TMJ) anterior disc displacement.
The clinical trial randomly allocated forty patients. The (control group) patients received four intraarticular and masseteric DDN sessions, while the (study group) patients were subjected to the exact technique followed by Prolosolution injection. The baseline preoperative measurements included Maximal interincisal opening (MIO), auscultation of the presence of clicking, and Visual Analogue Scale (VAS), which were repeated for postoperative measurements after one, two, five, and eight months.
By the end of the study, all patients expressed apparent improvement in pain MIO and clicking. The inter- and intragroup comparison revealed that the pain score values of the control group after five and eight months were significantly higher than those of the study group. The study group demonstrated more significant MIO calibration than the control group, with insignificant differences between both groups regarding the presence of clicking at any time interval. The associations between clicking and VAS values, between clicking and MIO, and between VAS values and increased MIO were positive in the test group and negative in the control group.
Dextrose Prolotherapy and DDN were beneficial. However, Prolotherapy demonstrated more significant, sustained, and correlated long-term alleviation of symptoms and increased MIO.
The study assesses the sole effect of dextrose prolotherapy on relieving the signs of TMJ anterior disc displacement apart from the impact of the penetrating needle.
The study was registered on www.
gov (#: NCT05821985) by Ahmed Nagi Alghandour.
比较注射疗法与深部干针疗法（DDN）联合应用与DDN疗法对缓解颞下颌关节（TMJ）前盘移位症状的效果。
该临床试验随机分配了40名患者。（对照组）患者接受4次关节内和咬肌深部干针治疗，而（研究组）患者先接受相同技术治疗，随后注射普洛溶液。术前基线测量包括最大切牙间开口度（MIO）、弹响听诊以及视觉模拟量表（VAS），在术后1个月、2个月、5个月和8个月重复进行测量。
研究结束时，所有患者的疼痛、MIO和弹响均有明显改善。组间和组内比较显示，对照组在5个月和8个月后的疼痛评分值显著高于研究组。研究组的MIO校准比对照组更显著，两组在任何时间间隔的弹响情况差异不显著。试验组中弹响与VAS值之间、弹响与MIO之间以及VAS值与MIO增加之间的关联为正，而对照组为负。
葡萄糖注射疗法和深部干针疗法均有益处。然而，注射疗法在症状的长期缓解以及MIO增加方面表现出更显著、持续且相关的效果。
该研究评估了葡萄糖注射疗法在排除穿刺针影响之外对缓解TMJ前盘移位体征的单独作用。
该研究由艾哈迈德·纳吉·阿尔甘杜尔在www.CLINICALTRIALS.gov上注册（编号：NCT05821985）。
