• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

嘌呤和吡啶浓度的变化作为对单次全身冷冻刺激的反应。

Changes in the Concentration of Purine and Pyridine as a Response to Single Whole-Body Cryostimulation.

作者信息

Dudzinska Wioleta, Lubkowska Anna

机构信息

Institute of Biology, University of Szczecin, Szczecin, Poland.

Department of Functional Diagnostics and Physical Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.

出版信息

Front Physiol. 2021 Jan 27;12:634816. doi: 10.3389/fphys.2021.634816. eCollection 2021.

DOI:10.3389/fphys.2021.634816
PMID:33584352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7873528/
Abstract

To our knowledge, this is the first study in which we provide evidence that a single whole-body cryostimulation treatment leads to changes associated with erythrocyte energy metabolism. These changes are beneficial from the point of view of cellular bioenergetics, because they are associated with an increase in ATP concentration and erythrocyte energy potential expressed by an increase in the ATP/ADP and ATP/AMP ratios and the value of adenylate energy charge (AEC). In addition, as affected by cryogenic temperatures, there is a decrease in the concentration of purine catabolism products, i.e., inosine and hypoxanthine in the blood.

摘要

据我们所知，这是第一项提供证据表明单次全身冷冻刺激治疗会导致与红细胞能量代谢相关变化的研究。从细胞生物能量学的角度来看，这些变化是有益的，因为它们与ATP浓度的增加以及通过ATP/ADP和ATP/AMP比率的增加以及腺苷酸能量电荷（AEC）值所表示的红细胞能量潜力的增加有关。此外，受低温影响，血液中嘌呤分解代谢产物即肌苷和次黄嘌呤的浓度会降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaf7/7873528/7c1a950ac1aa/fphys-12-634816-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaf7/7873528/7c1a950ac1aa/fphys-12-634816-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaf7/7873528/7c1a950ac1aa/fphys-12-634816-g001.jpg

相似文献

1
Changes in the Concentration of Purine and Pyridine as a Response to Single Whole-Body Cryostimulation.嘌呤和吡啶浓度的变化作为对单次全身冷冻刺激的反应。
Front Physiol. 2021 Jan 27;12:634816. doi: 10.3389/fphys.2021.634816. eCollection 2021.
2
Influence of glucose in dialyzing fluid on purine concentrations in hemodialyzed patients with chronic renal failure.透析液中葡萄糖对慢性肾衰竭血液透析患者嘌呤浓度的影响。
Nephron Clin Pract. 2003;95(1):c31-6. doi: 10.1159/000073016.
3
Comparison of human erythrocyte purine nucleotide metabolism and blood purine and pyrimidine degradation product concentrations before and after acute exercise in trained and sedentary subjects.训练有素的受试者和久坐不动的受试者在急性运动前后人体红细胞嘌呤核苷酸代谢以及血液中嘌呤和嘧啶降解产物浓度的比较。
J Physiol Sci. 2018 May;68(3):293-305. doi: 10.1007/s12576-017-0536-x. Epub 2017 Apr 21.
4
The Effect of Training on Erythrocyte Energy Status and Plasma Purine Metabolites in Athletes.训练对运动员红细胞能量状态和血浆嘌呤代谢产物的影响。
Metabolites. 2019 Dec 19;10(1):5. doi: 10.3390/metabo10010005.
5
Plasma Concentration of Irisin and Brain-Derived-Neurotrophic Factor and Their Association With the Level of Erythrocyte Adenine Nucleotides in Response to Long-Term Endurance Training at Rest and After a Single Bout of Exercise.静息状态及单次运动后长期耐力训练对鸢尾素和脑源性神经营养因子血浆浓度及其与红细胞腺嘌呤核苷酸水平相关性的影响
Front Physiol. 2020 Jul 31;11:923. doi: 10.3389/fphys.2020.00923. eCollection 2020.
6
Effect of lead ions on rat erythrocyte purine content.铅离子对大鼠红细胞嘌呤含量的影响。
Biol Trace Elem Res. 2004 Sep;100(3):259-73. doi: 10.1385/BTER:100:3:259.
7
The effect of lead ions on the energy metabolism of human erythrocytes in vitro.铅离子对人红细胞体外能量代谢的影响。
Comp Biochem Physiol C Toxicol Pharmacol. 2003 Mar;134(3):403-16. doi: 10.1016/s1532-0456(03)00008-5.
8
Purine nucleotides and their metabolites in erythrocytes of streptozotocin diabetic rats.链脲佐菌素诱导的糖尿病大鼠红细胞中的嘌呤核苷酸及其代谢产物
Diabetes Metab. 2004 Dec;30(6):557-67. doi: 10.1016/s1262-3636(07)70155-6.
9
Whole-body cryostimulation in kayaker women: a study of the effect of cryogenic temperatures on oxidative stress after the exercise.皮划艇女运动员的全身冷冻刺激：一项关于低温对运动后氧化应激影响的研究。
J Sports Med Phys Fitness. 2009 Jun;49(2):201-7.
10
Myoadenylate deaminase deficiency. Functional and metabolic abnormalities associated with disruption of the purine nucleotide cycle.肌腺苷酸脱氨酶缺乏症。与嘌呤核苷酸循环中断相关的功能和代谢异常。
J Clin Invest. 1984 Mar;73(3):720-30. doi: 10.1172/JCI111265.

引用本文的文献

1
The Effect of Cold-Water Swimming on Energy Metabolism, Dynamics, and Mitochondrial Biogenesis in the Muscles of Aging Rats.冷水游泳对衰老大鼠肌肉能量代谢、动力学和线粒体生物发生的影响。
Int J Mol Sci. 2024 Apr 5;25(7):4055. doi: 10.3390/ijms25074055.
2
Red Blood Cells from Individuals with Lesch-Nyhan Syndrome: Multi-Omics Insights into a Novel S162N Mutation Causing Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency.莱施-奈恩综合征患者的红细胞：对导致次黄嘌呤-鸟嘌呤磷酸核糖转移酶缺乏的新型S162N突变的多组学见解。
Antioxidants (Basel). 2023 Aug 31;12(9):1699. doi: 10.3390/antiox12091699.
3
The Role of Nucleases Cleaving TLR3, TLR7/8 and TLR9 Ligands, Dicer RNase and miRNA/piRNA Proteins in Functional Adaptation to the Immune Escape and Xenophagy of Prostate Cancer Tissue.

本文引用的文献

1
Plasma Concentration of Irisin and Brain-Derived-Neurotrophic Factor and Their Association With the Level of Erythrocyte Adenine Nucleotides in Response to Long-Term Endurance Training at Rest and After a Single Bout of Exercise.静息状态及单次运动后长期耐力训练对鸢尾素和脑源性神经营养因子血浆浓度及其与红细胞腺嘌呤核苷酸水平相关性的影响
Front Physiol. 2020 Jul 31;11:923. doi: 10.3389/fphys.2020.00923. eCollection 2020.
2
The Effect of Training on Erythrocyte Energy Status and Plasma Purine Metabolites in Athletes.训练对运动员红细胞能量状态和血浆嘌呤代谢产物的影响。
Metabolites. 2019 Dec 19;10(1):5. doi: 10.3390/metabo10010005.
3
核酸酶在 TLR3、TLR7/8 和 TLR9 配体、Dicer RNA 酶和 miRNA/piRNA 蛋白功能适应前列腺癌组织免疫逃逸和异噬中的作用。
Int J Mol Sci. 2022 Dec 28;24(1):509. doi: 10.3390/ijms24010509.
Shortage of Cellular ATP as a Cause of Diseases and Strategies to Enhance ATP.
细胞内三磷酸腺苷（ATP）短缺作为疾病病因及增强ATP的策略
Front Pharmacol. 2019 Feb 19;10:98. doi: 10.3389/fphar.2019.00098. eCollection 2019.
4
Whole body and partial body cryotherapies - lessons from human practice and possible application for horses.全身和局部低温疗法——来自人类实践的经验教训及对马匹的可能应用
BMC Vet Res. 2018 Dec 12;14(1):394. doi: 10.1186/s12917-018-1679-6.
5
Effects of Acute Cold Stress on Liver -GlcNAcylation and Glycometabolism in Mice.急性冷应激对小鼠肝糖基化和糖代谢的影响。
Int J Mol Sci. 2018 Sep 18;19(9):2815. doi: 10.3390/ijms19092815.
6
ATP Content and Cell Viability as Indicators for Cryostress Across the Diversity of Life.ATP含量和细胞活力作为衡量生命多样性中低温胁迫的指标。
Front Physiol. 2018 Jul 17;9:921. doi: 10.3389/fphys.2018.00921. eCollection 2018.
7
The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide Levels.mTORC1 信号网络感知细胞内嘌呤核苷酸水平的变化。
Cell Rep. 2017 Oct 31;21(5):1331-1346. doi: 10.1016/j.celrep.2017.10.029.
8
Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage.缺氧调节嘌呤补救途径，并降低冷藏保存过程中红细胞和上清液中次黄嘌呤的水平。
Haematologica. 2018 Feb;103(2):361-372. doi: 10.3324/haematol.2017.178608. Epub 2017 Oct 27.
9
NAD(H) and NADP(H) Redox Couples and Cellular Energy Metabolism.NAD(H) 和 NADP(H) 氧化还原对与细胞能量代谢。
Antioxid Redox Signal. 2018 Jan 20;28(3):251-272. doi: 10.1089/ars.2017.7216. Epub 2017 Jul 28.
10
Local cryotherapy minimally impacts the metabolome and transcriptome of human skeletal muscle.局部冷冻疗法对人体骨骼肌的代谢组和转录组的影响极小。
Sci Rep. 2017 May 25;7(1):2423. doi: 10.1038/s41598-017-02754-5.