van Aken Bernice C, Bakia Ayuk, Wierdsma André I, Voskes Yolande, Van Weeghel Jaap, van Bussel Evelyn M M, Hagestein Carla, Ruissen Andrea M, Leendertse Pien, Sewbalak Wishal V, van der Draai Daphne A, Hammink Alice, Mandos M E, van der Gaag Mark, Bonebakker Annette E, Van Der Feltz-Cornelis Christina M, Mulder Cornelis L
Department of Psychiatry, Erasmus MC, Epidemiological and Social Psychiatric Research Institute, Rotterdam, Netherlands.
Department of Ethics, Law and Humanities, Amsterdam UMC, Amsterdam, Netherlands.
Front Psychiatry. 2021 Jan 12;11:609530. doi: 10.3389/fpsyt.2020.609530. eCollection 2020.
Recovery is a multidimensional concept, including symptomatic, functional, social, as well as personal recovery. The present study aims at exploring psychosocial and biological determinants of personal recovery, and disentangling time-dependent relationships between personal recovery and the other domains of recovery in a sample of people with a psychotic disorder. A cohort study is conducted with a 10-year follow-up. Personal recovery is assessed using the Recovering Quality of Life Questionnaire (ReQoL) and the Individual Recovery Outcomes Counter (I.ROC). Other domains of recovery are assessed by the Positive and Negative Symptom Scale Remission (PANSS-R), the BRIEF-A and the Social Role Participation Questionnaire-Short version (SRPQ) to assess symptomatic, functional and societal recovery, respectively. In addition, multiple biological, psychological, and social determinants are assessed. This study aims to assess the course of personal recovery, and to find determinants and time-dependent relationships with symptomatic, functional and societal recovery in people with a psychotic disorder. Strengths of the study are the large number of participants, long duration of follow-up, multiple assessments over time, extending beyond the treatment trajectory, and the use of a broad range of biological, psychological, and social determinants.
康复是一个多维度的概念，包括症状缓解、功能恢复、社会融入以及个人康复。本研究旨在探索个人康复的心理社会和生物学决定因素，并在一组精神病患者样本中厘清个人康复与其他康复领域之间的时间依赖关系。开展了一项为期10年随访的队列研究。使用生活质量恢复问卷（ReQoL）和个体康复结果计数器（I.ROC）评估个人康复情况。分别通过阳性和阴性症状量表缓解版（PANSS-R）、简明症状问卷（BRIEF-A）和社会角色参与问卷简版（SRPQ）评估康复的其他领域，以分别评估症状缓解、功能恢复和社会康复情况。此外，还评估了多种生物学、心理和社会决定因素。本研究旨在评估个人康复的进程，并找出精神病患者中个人康复与症状缓解、功能恢复和社会康复之间的决定因素及时间依赖关系。本研究的优势在于参与者数量众多、随访时间长、随时间进行多次评估（涵盖治疗轨迹之外的时间）以及使用了广泛的生物学、心理和社会决定因素。
