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精神障碍患者的执行功能与个人康复之间的关联

The Association Between Executive Functioning and Personal Recovery in People With Psychotic Disorders.

作者信息

van Aken B C, Wierdsma A I, Voskes Y, Pijnenborg G H M, van Weeghel J, Mulder C L

机构信息

Department of Psychiatry, Erasmus MC, Epidemiological and Social Psychiatric Research Institute, Rotterdam, the Netherlands.

Department of Ethics, Law and Humanities, Amsterdam UMC, Amsterdam, the Netherlands.

出版信息

Schizophr Bull Open. 2022 Mar 7;3(1):sgac023. doi: 10.1093/schizbullopen/sgac023. eCollection 2022 Jan.

Abstract

BACKGROUND

Recovery in psychotic disorder patients is a multidimensional concept that can include personal, symptomatic, societal, and functional recovery. Little is known about the associations between personal recovery (PR) and functional recovery (FR). FR involves a person's ability to recover or compensate for impaired cognition, such as executive functions, and the loss of skills.

METHOD

In this cross-sectional study (the UP'S study), we used measures of executive functioning and personal recovery to assess a cohort of people with a psychotic disorder. PR was measured using the Recovering Quality of Life (ReQOL) and Individual Recovery Outcomes (I.ROC). FR was assessed using two forms of assessment. The Behavioral Rating Inventory of Executive Functioning Adult version (BRIEF-A) was used for self-rated executive functioning, and the Tower of London (TOL) for performance-based executive functioning. Regression models were calculated between executive functioning (BRIEF-A and TOL) and PR (ReQOL and I.ROC). Model selection was based on the Wald test.

RESULTS

The study included data on 260 participants. While total scores of BRIEF-A had a small negative association with those of the ReQOL (β = -0.28, > .001) and the I.ROC (β = -0.41, > .001), TOL scores were not significantly associated with the ReQOL scores (β = 0.03, = .76) and the I.ROC scores (β = 0.17, = 0.17).

CONCLUSION

Self-reported EF, which measures the accomplishment of goal pursuit in real life was associated with PR. However, processing efficiency and cognitive control as measured by performance-based EF were not.

摘要

背景

精神障碍患者的康复是一个多维度的概念,包括个人、症状、社会和功能康复。关于个人康复(PR)与功能康复(FR)之间的关联,我们所知甚少。功能康复涉及一个人恢复或补偿受损认知(如执行功能)以及技能丧失的能力。

方法

在这项横断面研究(UP'S研究)中,我们使用执行功能和个人康复的测量方法来评估一组精神障碍患者。使用生活质量恢复量表(ReQOL)和个人康复结果量表(I.ROC)来测量个人康复。功能康复通过两种评估形式进行评估。执行功能行为评定量表成人版(BRIEF - A)用于自评执行功能,伦敦塔测试(TOL)用于基于表现的执行功能评估。计算执行功能(BRIEF - A和TOL)与个人康复(ReQOL和I.ROC)之间的回归模型。模型选择基于 Wald 检验。

结果

该研究纳入了260名参与者的数据。虽然BRIEF - A的总分与ReQOL的总分呈小的负相关(β = -0.28,P >.001)以及与I.ROC的总分呈负相关(β = -0.41,P >.001),但TOL分数与ReQOL分数(β = 0.03,P =.76)和I.ROC分数(β = 0.17,P = 0.17)无显著相关性。

结论

自我报告的执行功能,即衡量现实生活中目标追求的完成情况,与个人康复相关。然而,基于表现的执行功能所测量的处理效率和认知控制则不然。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/743f/11206059/cc630e8de1fb/sgac023_fig1.jpg

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