Department of Psychology, University of Toronto Scarborough, Toronto, Ontario, Canada.
Greater Manchester Mental Health NHS Foundation Trust, Manchester, UK; School of Psychological Sciences, University of Manchester, Manchester, UK.
Schizophr Res. 2020 Sep;223:112-118. doi: 10.1016/j.schres.2020.06.026. Epub 2020 Jun 30.
Recovery from psychosis is increasingly being viewed as a combination of symptomatic, functional, and personal recovery. Negative and depressive symptoms have been linked to community functioning, and negative affect has been linked to personal recovery. The current study examines differential associations of symptoms with functional and personal recovery, and the interaction of cognitive and emotional components of psychotic experiences in predicting recovery.
Baseline data from four studies of individuals with schizophrenia-spectrum disorders were amalgamated for the current analyses. All studies utilized the Positive and Negative Syndrome Scale, Psychotic Symptom Rating Scale, Personal and Social Performance Scale, and the Questionnaire about the Process of Recovery.
971 individuals participated across the four studies. Affective symptoms were most strongly associated with personal recovery, accounting for 30% of the variance in personal recovery and only 2% of the variance in objective functioning. Negative and disorganized symptoms were related to both functional and personal recovery, excitement symptoms were only related to personal recovery, and broad measures of positive symptoms were not associated with either functional or personal recovery. Cognitive interpretations of psychotic experiences were more strongly related to objective functioning, and emotional components of psychotic experiences were more strongly related to personal recovery; cognitive interpretations moderated the relationship between emotional characteristics and recovery measures.
Functional and personal recovery are distinct domains of recovery with differential relationships to symptomatology. Interventions that target cognitive interpretations of psychotic experiences and negative affect may be more likely to affect multiple domains of recovery.
精神康复越来越被视为症状、功能和个人康复的结合。负面和抑郁症状与社区功能有关,而负面情绪与个人康复有关。本研究考察了症状与功能和个人康复的不同关联,以及精神体验的认知和情感成分的相互作用对预测康复的影响。
对四项精神分裂症谱系障碍个体研究的基线数据进行合并,用于当前分析。所有研究均采用阳性和阴性综合征量表、精神症状评定量表、个人和社会表现量表以及康复过程问卷。
四项研究共有 971 人参与。情感症状与个人康复的关联最强,占个人康复方差的 30%,仅占客观功能方差的 2%。阴性和紊乱症状与功能和个人康复均有关,兴奋症状仅与个人康复有关,广泛的阳性症状与功能或个人康复均无关。对精神体验的认知解释与客观功能的关联更强,而精神体验的情感成分与个人康复的关联更强;认知解释调节了情感特征与康复测量之间的关系。
功能和个人康复是康复的不同领域,与症状学有不同的关系。针对精神体验的认知解释和负性情绪的干预措施可能更有可能影响多个康复领域。