van Dam Victor S, Maas Britta D P J, Schermer Tjard R, van Benthem Peter-Paul G, Bruintjes Tjasse D
Apeldoorn Dizziness Centre, Gelre Hospital, Apeldoorn, Netherlands.
Department of Otorhinolaryngology and Head and Neck Surgery, Leiden University Medical Centre, Leiden, Netherlands.
Front Neurol. 2021 Jan 14;11:625776. doi: 10.3389/fneur.2020.625776. eCollection 2020.
This prospective cohort study determined which questions in patient history are most likely to identify symptoms that are independently associated with a diagnosis of benign paroxysmal positional dizziness (BPPV) in patients presenting with dizziness, and to evaluate whether the patient's age and type of BPPV are of influence. We included adult patients with dizziness referred to our dizziness center, Apeldoorn, the Netherlands, from December 2018 to November 2019. All patients completed a questionnaire, underwent vestibular testing and received a diagnosis. Symptoms strongly suggesting BPPV were tested with multivariable analysis to determine their independent associations with BPPV. Subgroup analysis was performed for patient age, and the type of BPPV. We included a total of 885 patients, 113 of whom (13%) were diagnosed with BPPV. The duration of dizziness spells <1 min (Q2) and dizziness provoked by rolling over in bed (Q4) were independently associated with the diagnosis BPPV. Q2 showed a sensitivity of 43%, and a specificity of 75%; Q4 scored 81% and 68%, respectively. Overall, the way patients perceived their dizziness (vertigo, light-headedness or instability) was not independently associated with the diagnosis BPPV. In younger patients, light-headedness and instability decreased the likelihood of BPPV compared to vertigo. The most reliable predictors for BPPV in patient history are a short duration of the dizziness spell and provocation of dizziness by rolling over in bed. Unlike younger patients, elderly patients with BPPV do not only perceive the dizziness as vertigo, but also as a feeling of instability.
这项前瞻性队列研究确定了在头晕患者中,病史中的哪些问题最有可能识别出与良性阵发性位置性眩晕(BPPV)诊断独立相关的症状,并评估患者的年龄和BPPV类型是否有影响。我们纳入了2018年12月至2019年11月转诊至荷兰阿珀尔多恩头晕中心的成年头晕患者。所有患者均完成了一份问卷,接受了前庭测试并获得了诊断。对强烈提示BPPV的症状进行多变量分析,以确定它们与BPPV的独立关联。对患者年龄和BPPV类型进行了亚组分析。我们共纳入了885例患者,其中113例(13%)被诊断为BPPV。头晕发作持续时间<1分钟(问题2)和在床上翻身诱发的头晕(问题4)与BPPV诊断独立相关。问题2的敏感性为43%,特异性为75%;问题4的敏感性和特异性分别为81%和68%。总体而言,患者对头晕的感知方式(眩晕、头晕或不稳)与BPPV诊断无独立关联。在年轻患者中,与眩晕相比,头晕和不稳降低了BPPV的可能性。病史中BPPV最可靠的预测因素是头晕发作持续时间短和在床上翻身诱发头晕。与年轻患者不同,老年BPPV患者不仅将头晕感知为眩晕,还感知为不稳感。