Sirtoli Vinicius G, Morcelles Kaue F, Vincence Volney C
Department of Electrical Engineering, Santa Catarina State University (UDESC), Joinville, Brazil.
J Electr Bioimpedance. 2018 Dec 19;9(1):59-71. doi: 10.2478/joeb-2018-0011. eCollection 2018 Jan.
Bioimpedance measurement systems often use the Howland current sources to excite the biological material under study. Usually, difference or instrumentation amplifiers are used to measure the resulting voltage drop on this material. In these circuits, common mode voltage appears as artifacts in the measurement. Most researches on current sources are focused on improving the output impedance, letting other characteristics aside. In this paper, it is made a brief review on the load common mode voltage and output swing of various topologies of Howland current sources. Three circuits are proposed to reduce load common mode voltage and enhance load capability by using a fully differential amplifier as active component. These circuits are equated, simulated and implemented. The three proposed circuits were able to deliver an output current with cut-off frequency (-3dB) higher than 1 MHz for loads as big as 4.7 kΩ. The worst measured load common mode voltage was smaller than 24 mV for one of the circuits and smaller than 8 mV for the other two. Consequently, it could be obtained increases in the Common Mode Rejection Ratio (CMRR) up to 60 dB when compared to the Enhanced Howland Current Source (EHCS).
生物阻抗测量系统通常使用霍兰德电流源来激励所研究的生物材料。通常,采用差分放大器或仪表放大器来测量该材料上产生的电压降。在这些电路中,共模电压会作为测量中的伪像出现。大多数关于电流源的研究都集中在提高输出阻抗上,而忽略了其他特性。本文简要回顾了各种拓扑结构的霍兰德电流源的负载共模电压和输出摆幅。提出了三种电路,通过使用全差分放大器作为有源元件来降低负载共模电压并提高负载能力。对这些电路进行了等效、仿真和实现。所提出的三种电路能够为高达4.7 kΩ的负载提供截止频率(-3dB)高于1 MHz的输出电流。其中一个电路测得的最差负载共模电压小于24 mV,另外两个小于8 mV。因此,与增强型霍兰德电流源(EHCS)相比,共模抑制比(CMRR)可提高至60 dB。