Braga Joana, Pereira Francisca, Fernandes Cristiana, Silva Marinha, Boncoraglio Teresa, Oliveira Carlos
Department of Internal Medicine, Hospital Santa Maria Maior, Barcelos, Portugal.
Eur J Case Rep Intern Med. 2021 Jan 18;8(1):002219. doi: 10.12890/2021_002219. eCollection 2021.
Splenosis is a benign condition which results from the self-implantation of splenic tissue on intra or extraperitoneal surfaces, after splenic trauma or splenectomy. Patients are usually asymptomatic but may present with varied symptoms related to the implantation site. The diagnosis is a challenge because abdominal splenosis can mimic several diseases, including neoplasm. The gold standard examination for its diagnosis is scintigraphy with 99mTc-labelled heat-denatured erythrocyte. When splenosis is found in an asymptomatic patient, surgical removal is not indicated. A 57-year-old male patient presented with sporadic epigastric pain and a suspected mass in the recto-sigmoid transition. Abdominal ultrasound, CT and MRI identified this mass, its characteristics and location, but failed to distinguish its nature. However, given the patient's past history of splenectomy and because the mass showed a similar sign to that of the splenic parenchyma, a hypothesis of abdominal splenosis was raised, which was confirmed by scintigraphy with 99mTc-labelled heat-denatured erythrocyte. In this case, the diagnosis was obtained before the patient was subjected to more invasive procedures, which are associated with high morbidity, and, as in most cases, no targeted intervention was necessary.
Increasing numbers of cases of abdominal trauma will result in more frequent splenosis.Diagnosis is sometimes complex as splenosis mimics several diseases.The usual complementary imaging studies often fail to diagnose this entity so clinical suspicion is fundamental for correct diagnosis and treatment.
脾组织自体移植是一种良性疾病,它是在脾外伤或脾切除术后,脾组织在腹膜内或腹膜外表面自体植入所致。患者通常无症状,但可能出现与植入部位相关的各种症状。诊断具有挑战性,因为腹部脾组织自体移植可模仿多种疾病,包括肿瘤。其诊断的金标准检查是99mTc标记热变性红细胞闪烁扫描。当在无症状患者中发现脾组织自体移植时,不建议手术切除。一名57岁男性患者出现散发性上腹部疼痛,在直肠乙状结肠移行处疑似有肿块。腹部超声、CT和MRI确定了该肿块、其特征和位置,但未能区分其性质。然而,鉴于患者既往有脾切除术史,且肿块表现出与脾实质相似的征象,于是提出腹部脾组织自体移植的假说,99mTc标记热变性红细胞闪烁扫描证实了这一假说。在这种情况下,在患者接受更具侵入性且并发症发生率高的手术之前就做出了诊断,并且在大多数情况下,无需进行针对性干预。
腹部外伤病例的增加将导致脾组织自体移植更为常见。由于脾组织自体移植可模仿多种疾病,诊断有时较为复杂。常用的辅助影像学检查往往无法诊断该病,因此临床怀疑对于正确诊断和治疗至关重要。