Manna Utsab, Portis Bobby, Egboluche Tochukwu K, Nafis Muhammad, Hossain Md Alamgir
Department of Chemistry, Physics and Atmospheric Sciences, Jackson State University, Jackson, MS, United States.
Front Chem. 2021 Jan 29;8:575701. doi: 10.3389/fchem.2020.575701. eCollection 2020.
Two rationally designed 4-nitrophenyl-based molecular clefts functionalized with thiourea ( ) and urea ( ) have been synthesized and studied for a variety of anions by UV-Vis and colorimetric techniques in DMSO. Results from the binding studies suggest that both and bind halides showing the order: fluoride > chloride > bromide > iodide; and oxoanions showing the order: dihydrogen phosphate > hydrogen sulfate > nitrate > perchlorate. Each receptor has been shown to form a 1:1 complex with an anion hydrogen bonding interactions, displaying distinct color change for fluoride and dihydrogen phosphate in solution. As compared to the urea-based receptor , the thiourea-based receptor exhibits stronger affinity for anions due the presence of more acidic thiourea functional groups.
已合成了两种经合理设计的、用硫脲（ ）和尿素（ ）官能化的基于4-硝基苯基的分子裂缝，并通过紫外可见光谱和比色技术在二甲基亚砜中对多种阴离子进行了研究。结合研究结果表明， 和 均能结合卤化物，其顺序为：氟化物＞氯化物＞溴化物＞碘化物；结合含氧阴离子的顺序为：磷酸二氢根＞硫酸氢根＞硝酸根＞高氯酸根。已证明每种受体与阴离子通过氢键相互作用形成1:1配合物，在溶液中对氟化物和磷酸二氢根显示出明显的颜色变化。与基于尿素的受体 相比，基于硫脲的受体 由于存在更多酸性的硫脲官能团而对阴离子表现出更强的亲和力。
