Daunaraite Karolina, Uvarovas Valentinas, Ulevicius Donatas, Sveikata Tomas, Petryla Giedrius, Kurtinaitis Jaunius, Satkauskas Igoris
Vilnius University, Institute of Clinical Medicine, Faculty of Medicine, Vilnius LT-08661, Lithuania.
Department of Orthopedics and Traumatology, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius LT-08661, Lithuania.
World J Clin Cases. 2021 Feb 6;9(4):830-837. doi: 10.12998/wjcc.v9.i4.830.
Haematogenous osteomyelitis is an extremely rare disease occurring in adults, especially in developed countries. It is clearly a systemic infection, because bacteraemia spreads over proximal and distal long bones or paravertebral plexuses, resulting in acute or chronic bone infection and destruction.
A 46-year-old Caucasian male was complaining of a left thigh pain. It is known from the anamnesis that the patient developed severe pneumonia three months ago before the onset of these symptoms. The patient was diagnosed with haematogenous osteomyelitis, which developed a turbulent course and required complex combination therapy. The primary pathogen is thought to be , which caused pneumonia before the onset of signs of osteomyelitis. Unfortunately, due to the complexity of identifying anaerobes and contributing nosocomial infections, the primary pathogen was not extracted immediately. After the manifestation of this disease, pathological fractures occurred in both femurs, as well as purulent processes in the lungs and molars accompanied. The patient received broad-spectrum antibiotic therapy and countless amounts of orthopaedic and reconstructive surgeries, but no positive effect was observed. The patient underwent osteosynthesis using an Ilizarov's external fixation apparatus, re-fixations, external AO, debridements, intrame-dullary osteosynthesis with a silver-coated intramedullary nail, abscessotomies. The right femur healed completely after the pathological fracture and osteomyelitis did not recur. Left femur could not be saved due to non-healing, knee contracture and bone destruction. After almost three years of struggle, it was decided to amputate the left limb, after which the signs of osteomyelitis no longer appeared.
To sum it all up, complicated or chronic osteomyelitis requires surgery to remove the infected tissue and bone. Osteomyelitis surgery prevents the infection from spreading further or getting even worse up to such condition that amputation is the only option left.
血源性骨髓炎是一种在成年人中极为罕见的疾病,尤其是在发达国家。它显然是一种全身性感染,因为菌血症会扩散到近端和远端长骨或椎旁丛,导致急性或慢性骨感染和破坏。
一名46岁的白种男性主诉左大腿疼痛。从病史中得知,该患者在这些症状出现前三个月患了严重肺炎。患者被诊断为血源性骨髓炎,病情发展曲折,需要复杂的联合治疗。主要病原体被认为是 ,它在骨髓炎症状出现前引发了肺炎。不幸的是,由于厌氧菌鉴定和医院获得性感染因素复杂,主要病原体未能立即查出。该病出现后,双侧股骨均发生病理性骨折,同时伴有肺部和磨牙的化脓性病变。患者接受了广谱抗生素治疗以及无数次骨科和重建手术,但未见明显效果。患者接受了使用伊里扎洛夫外固定架的骨固定术、再次固定术、AO外固定术、清创术、带银涂层髓内钉的髓内骨固定术、脓肿切开术。右侧股骨病理性骨折后完全愈合,骨髓炎未复发。左侧股骨因不愈合、膝关节挛缩和骨质破坏无法保住。经过近三年的抗争,决定对左下肢进行截肢,截肢后骨髓炎症状不再出现。
综上所述,复杂或慢性骨髓炎需要手术切除感染组织和骨头。骨髓炎手术可防止感染进一步扩散或恶化到截肢成为唯一选择的地步。