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单孔与三孔电视辅助胸腔镜手术治疗非小细胞肺癌的回顾性研究。

Uniportal versus three-port video-assisted thoracoscopic surgery for non-small cell lung cancer: A retrospective study.

机构信息

Department of Thoracic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

Anhui University of Traditional Chinese Medicine, Hefei, China.

出版信息

Thorac Cancer. 2021 Apr;12(8):1147-1153. doi: 10.1111/1759-7714.13882. Epub 2021 Feb 14.

Abstract

BACKGROUND

To investigate the uniportal video-assisted thoracoscopic surgery (VATS) technique and safety of non-small cell lung cancer (NSCLC) patients treated with uniportal and three-port VATS.

METHODS

We retrospectively evaluated 146 consecutive patients with NSCLC who underwent VATS lobectomy between January 2018 and May 2018. The general clinical date, perioperative data and life quality were individually compared and analyzed between the two groups.

RESULTS

Intraoperative blood loss was significantly lower in the uniportal than in the three-port group (p = 0.035), and significantly shorter chest tube drainage and postoperative hospital stay durations were found in the uniportal than in the three-port group (p = 0.022 and p = 0.008). The postoperative 24 and 72 h numerical rating scale (NRS) scores were significantly lower in the uniportal group than in the three-port group (p < 0.001 and p < 0.001). There were no significant differences between the two groups in the number or stations of total lymph node dissected (p = 0.222 and p = 0.159). There were no significant differences between the two groups in the postoperative total or respiratory complications (p = 0.917 and p = 0.930).

CONCLUSIONS

Uniportal VATS is a safe and effective alternative for patients with NSCLC. It is a preferable option for appropriate cases as it is conducive to patients' postoperative recovery and quality of life.

摘要

背景

研究单孔与三孔电视辅助胸腔镜手术(VATS)治疗非小细胞肺癌(NSCLC)患者的技术和安全性。

方法

我们回顾性评估了 2018 年 1 月至 2018 年 5 月期间接受 VATS 肺叶切除术的 146 例连续 NSCLC 患者。分别比较和分析两组的一般临床资料、围手术期数据和生活质量。

结果

单孔组术中出血量明显低于三孔组(p = 0.035),单孔组的胸腔引流管和术后住院时间明显短于三孔组(p = 0.022 和 p = 0.008)。单孔组术后 24 小时和 72 小时数字评分量表(NRS)评分明显低于三孔组(p < 0.001 和 p < 0.001)。两组总淋巴结清扫的数量或站数无显著差异(p = 0.222 和 p = 0.159)。两组术后总并发症或呼吸系统并发症发生率无显著差异(p = 0.917 和 p = 0.930)。

结论

单孔 VATS 是治疗 NSCLC 患者的安全有效的方法。对于合适的病例,它是一种更好的选择,因为它有利于患者的术后恢复和生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6039/8046032/04dd4675cb64/TCA-12-1147-g002.jpg

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