Mikheev R K, Andreeva E N, Sheremetyeva E V, Absatarova Yu S, Ponomareva T A, Grigoryan O R
Endocrinology Research Centre.
Endocrinology Research Centre; Moscow State University of Medicine and Dentistry.
Probl Endokrinol (Mosk). 2021 Jan 22;67(1):69-75. doi: 10.14341/probl12710.
One of the new directions in the study of reproductive disorders in obese women is the effect and receptor sensitivity of melatonin on the gonadotropic function of the pituitary gland and ovariogenesis, taking into account the chronology of «light pollution». At the present stage, there is very little literature on the influence of the aspects of «light pollution» on the problem of obesity and reproductive disorders in the literature. This review is an attempt to combine the above problem in terms of the impact of «light pollution» and the level of receptor sensitivity of melatonin in women of reproductive age with obesity. The literature search was carried out in Russian (eLibrary, CyberLeninka.ru) and international (PubMed, Cochrane Library) databases in Russian and English. Free access to the full text of the articles was a priority. The selection of sources was prioritized for the period from 2015 to 2019. However, given the insufficient knowledge of the chosen topic, the choice of sources was dated from 1992. The work was carried out as part of the study «Central and peripheral pathophysiological mechanisms of development of adipose tissue diseases, taking into account clinical and hormonal characteristics» 2020-2022.
肥胖女性生殖系统紊乱研究的新方向之一是,考虑到“光污染”的时间顺序,褪黑素对垂体促性腺功能和卵巢发生的影响及受体敏感性。现阶段,文献中关于“光污染”对肥胖和生殖系统紊乱问题影响的内容非常少。这篇综述试图从“光污染”的影响以及肥胖育龄女性褪黑素受体敏感性水平方面,将上述问题结合起来。文献检索在俄罗斯(eLibrary、CyberLeninka.ru)和国际(PubMed、Cochrane Library)数据库中以俄语和英语进行。优先获取文章全文。文献来源的选择优先考虑2015年至2019年期间。然而,鉴于所选主题的知识不足,文献来源的选择可追溯到1992年。这项工作是作为“考虑临床和激素特征的脂肪组织疾病发生的中枢和外周病理生理机制”研究(2020 - 2022年)的一部分开展的。