Postoperative spindle-cell nodule of the endometrium.

The clinical and pathologic features of a case of postoperative spindle-cell nodule within the endometrium are reported, a lesion hitherto undescribed in this site. The nodule was found in the hysterectomy specimen from a 75-year-old woman, 2 1/2 weeks after a dilatation and curettage had revealed a well-differentiated endometrial adenocarcinoma. On histologic examination, the lesion consisted of a densely cellular proliferation of mitotically active spindle cells, which was initially interpreted as sarcoma. Postoperative spindle-cell nodules of the genitourinary tract are reparative proliferations of fibroblastic-type cells that should be distinguished from sarcoma on histologic examination.