通过连续芳炔反应合成多样的二芳基硫化物。
Diverse diaryl sulfide synthesis through consecutive aryne reactions.
机构信息
Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.
出版信息
Chem Commun (Camb). 2021 Mar 11;57(21):2621-2624. doi: 10.1039/d0cc08373a.
PMID:33586722
Abstract
An efficient method to synthesize diaryl sulfides with structural diversity is disclosed. Demethylative hydrothiolation of aryne intermediates generated from o-iodoaryl triflates with methylthio-substituted o-silylaryl triflates and further aryne reactions afford diverse diaryl sulfides.
摘要
本文公开了一种高效合成具有结构多样性的二芳基硫化物的方法。间碘芳基三氟甲磺酸酯与甲硫基取代的邻硅基芳基三氟甲磺酸酯生成的芳基炔中间体进行脱甲基硫醇化反应，然后进一步进行芳炔反应，可得到多种二芳基硫化物。
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