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真实世界证据:骨科研究中使用的真实世界数据来源综述。

Real-World Evidence: A Review of Real-World Data Sources Used in Orthopaedic Research.

作者信息

Hak David J, Mackowiak John I, Irwin Debra E, Aldridge Molly L, Mack Christina D

机构信息

Hughston Orthopaedic Trauma Surgeons, Central Florida Regional Hospital, Sanford, FL.

Center for Outcomes Research, Cedar Point NC.

出版信息

J Orthop Trauma. 2021 Mar 1;35(Suppl 1):S6-S12. doi: 10.1097/BOT.0000000000002038.

DOI:10.1097/BOT.0000000000002038
PMID:33587540
Abstract

Real-world data (RWD) play an increasingly important role in orthopaedics as demonstrated by the rapidly growing number of publications using registry, administrative, and other databases. Each type of RWD source has its strengths and weaknesses, as does each specific database. Linkages between real-world data sets provide even greater utility and value for research than single data sources. The unique qualities of an RWD data source and all data linkages should be considered before use. Close attention to data quality and use of appropriate analysis methods can help alleviate concerns about validity of orthopaedic studies using RWD. This article describes the main types of RWD used in orthopaedics and provides brief descriptions and a sample listing of publications from selected, key data sources.

摘要

现实世界数据(RWD)在骨科领域发挥着越来越重要的作用,这一点从使用登记处、行政和其他数据库的出版物数量迅速增长就可以看出。每种类型的RWD来源都有其优缺点,每个特定数据库也是如此。现实世界数据集之间的关联为研究提供的效用和价值比单一数据源更大。在使用之前,应考虑RWD数据源的独特性质以及所有数据关联。密切关注数据质量并使用适当的分析方法有助于减轻对使用RWD的骨科研究有效性的担忧。本文描述了骨科中使用的主要RWD类型,并对选定的关键数据源的出版物进行了简要描述和示例列举。

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