Gastroenterology and Hepatology Department, Virgen Macarena University Hospital, Seville, Spain.
Gastroenterology Department, Virgen Macarena University Hospital, Seville, Spain.
Liver Int. 2021 May;41(5):928-933. doi: 10.1111/liv.14824. Epub 2021 Mar 8.
Hepatitis C virus (HCV) one-step diagnosis improves recovery in patients with active infection. However, patients with previous anti-HCV+ may be excluded. We aimed to identify and retrieve non-referred or lost-to-follow-up HCV-infected patients. All anti-HCV+ patients seen in our hospital between 2013 and 2018 were included. In the first phase, we identified anti-HCV+ patients who were not referred to the Gastroenterology Unit (GU) or lost-to-follow-up. In the second phase, recovered patients were invited for a one-step visit for liver evaluation. A total of 1330 anti-HCV+ patients were included: 21.7% had not been referred to GU, and 23.1% were lost-to-follow-up. In the second phase, 49.6% of patients were contacted, and 92.8% attended a medical consultation: 62.7% had active infection, 92.2% were treated, and 86.5% achieved SVR (ITT). We concluded that screening microbiological data and referring unidentified patients with active HCV infection directly to specialists is an effective tool in achieving HCV microelimination.
丙型肝炎病毒 (HCV) 一步诊断可提高活动性感染患者的康复率。然而，既往抗-HCV+的患者可能会被排除在外。我们旨在发现和检索未转诊或失访的 HCV 感染患者。我们纳入了 2013 年至 2018 年期间在我院就诊的所有抗-HCV+患者。在第一阶段，我们确定了未转诊至胃肠病科（GU）或失访的抗-HCV+患者。在第二阶段，我们邀请康复患者进行一步就诊以进行肝脏评估。共纳入 1330 例抗-HCV+患者：21.7%未转诊至 GU，23.1%失访。在第二阶段，我们联系了 49.6%的患者，92.8%的患者参加了医疗咨询：62.7%的患者有活动性感染，92.2%的患者接受了治疗，86.5%的患者达到了 SVR（ITT）。我们得出结论，筛查微生物数据并将未识别的活动性 HCV 感染患者直接转诊给专家是实现 HCV 消除的有效工具。
