Department of Emergency and Critical Care Medicine, West China School of Public Health, West China Fourth Hospital, Sichuan University, Chengdu, China.
Am J Med Sci. 2021 Jul;362(1):92-98. doi: 10.1016/j.amjms.2021.02.010. Epub 2021 Feb 13.
This manuscript aimed to describe and analyze acute trimethyltin poisoning caused by exposure to polyvinyl chloride production and review the literature. Combined with an analysis of occupational hygiene survey data, the clinical data of 8 cases of acute trimethyltin poisoning were analyzed retrospectively. The clinical manifestations of acute trimethyltin poisoning are mainly related to central nervous system damage, hypokalemia and metabolic acidosis in patients with severe poisoning. Early positive potassium supplementation and symptomatic treatment are beneficial to the improvement of the condition. The early recognition of central nervous system manifestations and hypokalemia is beneficial for early diagnosis and correct treatment.
本手稿旨在描述和分析聚氯乙烯生产导致的急性三甲基锡中毒，并复习文献。结合职业卫生调查数据的分析，对 8 例急性三甲基锡中毒患者的临床资料进行回顾性分析。急性三甲基锡中毒的临床表现主要与中枢神经系统损伤有关，严重中毒患者伴有低钾血症和代谢性酸中毒。早期积极补钾和对症治疗有利于病情改善。早期识别中枢神经系统表现和低钾血症有利于早期诊断和正确治疗。
