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验证 MC-GPU 蒙特卡罗代码与 PENELOPE/penEasy 代码系统的一致性,并针对介入放射学和心脏病学中典型辐射质量和设置的实验条件进行基准测试。

Validation of the MC-GPU Monte Carlo code against the PENELOPE/penEasy code system and benchmarking against experimental conditions for typical radiation qualities and setups in interventional radiology and cardiology.

机构信息

Universitat Politècnica de Catalunya, Avda. Diagonal 647, 08028 Barcelona, Spain.

Universitat Politècnica de Catalunya, Avda. Diagonal 647, 08028 Barcelona, Spain.

出版信息

Phys Med. 2021 Feb;82:64-71. doi: 10.1016/j.ejmp.2021.01.075. Epub 2021 Feb 13.

Abstract

INTRODUCTION

Interventional procedures are associated with potentially high radiation doses to the skin. The 2013/59/EURATOM Directive establishes that the equipment used for interventional radiology must have a device or a feature informing the practitioner of relevant parameters for assessing patient dose at the end of the procedure. Monte Carlo codes of radiation transport are considered to be one of the most reliable tools available to assess doses. However, they are usually too time consuming for use in clinical practice. This work presents the validation of the fast Monte Carlo code MC-GPU for application in interventional radiology.

METHODOLOGIES

MC-GPU calculations were compared against the well-validated Monte Carlo simulation code PENELOPE/penEasy by simulating the organ dose distribution in a voxelized anthropomorphic phantom. In a second phase, the code was compared against thermoluminescent measurements performed on slab phantoms, both in a calibration laboratory and at a hospital.

RESULTS

The results obtained from the two simulation codes show very good agreement, differences in the output were within 1%, whereas the calculation time on the MC-GPU was 2500 times shorter. Comparison with measurements is of the order of 10%, within the associated uncertainty.

CONCLUSIONS

It has been verified that MC-GPU provides good estimates of the dose when compared to PENELOPE program. It is also shown that it presents very good performance when assessing organ doses in very short times, less than one minute, in real clinical set-ups. Future steps would be to simulate complex procedures with several projections.

摘要

简介

介入性操作会使皮肤受到潜在的高剂量辐射。2013/59/EURATOM 指令规定,用于介入放射学的设备必须配备一种设备或功能,以便在操作结束时向医生提供评估患者剂量的相关参数。辐射输运的蒙特卡罗代码被认为是评估剂量的最可靠工具之一。然而,它们通常在临床实践中使用过于耗时。本工作验证了用于介入放射学的快速蒙特卡罗代码 MC-GPU。

方法

通过模拟体素化人体模型中的器官剂量分布,将 MC-GPU 的计算结果与经过良好验证的蒙特卡罗模拟代码 PENELOPE/penEasy 进行比较。在第二阶段,代码在校准实验室和医院的平板模型上与热释光测量进行了比较。

结果

两个模拟代码的结果非常吻合,输出差异在 1%以内,而 MC-GPU 的计算时间缩短了 2500 倍。与测量结果的比较在 10%左右,在相关的不确定性范围内。

结论

已经验证了 MC-GPU 在与 PENELOPE 程序比较时可以很好地估计剂量。还表明,它在非常短的时间内(不到一分钟)评估真实临床设置中的器官剂量时,具有非常好的性能。未来的步骤将是模拟具有多个投影的复杂程序。

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