The behavior of male and female Wistar rats pressing a lever for food is not affected by sex differences in food motivation.

Male rats both eat more and weigh more than females. Differences in food intake and body weight result, at least partly, from differences in gonadal hormone secretions. The present experiments were designed to investigate whether sex differences in food motivation might contribute to the behavioral differences observed when food-deprived male and female rats are exposed to appetitively motivated operant learning tasks. Male and female Wistar rats were exposed to different progressive ratio schedules of reinforcement which have been shown to generate reliable indices of 'motivational' conditions. In progressive ratio schedules, subjects are required to make a systematically increasing number of responses for each successive reinforcer, until the requirement becomes so large that the subjects stop responding. Expt. Ia was designed to investigate whether or not food-deprived males would be more motivated than food-deprived females to obtain food. Expt. Ib investigated whether gonadectomy might differentially affect food motivation of male and female rats exposed to a progressive ratio schedule of reinforcement. Motivational differences between males and females were not observed. Males and females obtained an equal number of reinforcers, while differences in the total number of responses and response rate were not observed. Gonadectomy did not affect the total number of responses in the final completed ratio. The results of the present experiments do therefore not support the hypothesis that sex differences in food motivation might underlie sex differences in behavior when food-deprived male and female rats are exposed to operant schedules of positive reinforcement.