Department of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, China.
Hunan Clinical Research Center of Ophthalmic Disease, Changsha, China.
BMC Ophthalmol. 2021 Feb 15;21(1):86. doi: 10.1186/s12886-021-01853-2.
The purpose of this study is to assess the absorption of subretinal fluid (SRF) after scleral buckling (SB) surgery for the treatment of rhegmatogenous retinal detachment (RRD). We also examined related factors that may affect the delayed absorption of SRF.
This retrospective study included patients who underwent successful SB surgery for the treatment of macula-off RRD and in which the retina was reattached after the surgery. The patients were categorized according to gender, duration, age, the number, and location of retinal breaks. Subfoveal choroidal thickness (SFCT), height of subretinal fluid (SRFH), and the choriocapillaris flow density (CCFD) within 3 × 3 mm macular fovea were included. Delayed absorption was determined by the SRF that remained unabsorbed for 3 months after the procedure. The endpoint was determined when the SRF could no longer be observed.
A total of 62 patients (63 eyes) were enrolled. In 35 eyes (56.45%) SRF was completely absorbed and in 28 (43.55%) eyes delayed absorption of SRF in macular areas was observed at 3 months after surgery. A young age (< 35 years), inferior retinal breaks were associated with good outcomes by applying multivariable analysis on the rate of SRF absorption after SB instead of gender, the number of breaks, and duration (p < 0.05). CCFD was significantly different between the SRF group and the non-SRF group after SB (0.66 ± 0.04% vs 0.63 ± 0.05%, P < 0.05). SRFH showed a moderate positive correlation with SFCT (r = 0.462, p = 0.000), however, using binary logistic regression analysis it was determined that SFCT was not related to the absorption of the SRF.
The absorption of SRF after SB may be correlated with choriocapillaris flow density. Age and location of breaks are significant factors affecting the absorption of SRF. The duration of disease is an uncertain factor due to several subjective reasons.
本研究旨在评估巩膜扣带术（SB）治疗孔源性视网膜脱离（RRD）后视网膜下液（SRF）的吸收情况。我们还研究了可能影响 SRF 延迟吸收的相关因素。
本回顾性研究纳入了接受 SB 手术成功治疗黄斑裂孔型 RRD 且术后视网膜复位的患者。根据性别、病程、年龄、视网膜裂孔数量和位置对患者进行分类。纳入黄斑中心凹 3×3mm 内的脉络膜厚度（SFCT）、视网膜下液高度（SRFH）和脉络膜毛细血管血流密度（CCFD）。术后 3 个月 SRF 仍未吸收定义为延迟吸收。当无法再观察到 SRF 时，确定终点。
共纳入 62 例（63 只眼）患者。35 只眼（56.45%）的 SRF 完全吸收，28 只眼（43.55%）的 SRF 在术后 3 个月时仍在黄斑区延迟吸收。多变量分析显示，与 SB 术后 SRF 吸收率相关的因素是年龄（<35 岁）而非性别、裂孔数量和病程（p<0.05），下象限视网膜裂孔与 SRF 吸收良好相关。与非 SRF 组相比，SB 术后 SRF 组的 CCFD 显著不同（0.66±0.04% vs 0.63±0.05%，P<0.05）。SRFH 与 SFCT 呈中度正相关（r=0.462，p=0.000），但二元逻辑回归分析显示 SFCT 与 SRF 吸收无关。
SB 术后 SRF 的吸收可能与脉络膜毛细血管血流密度有关。年龄和裂孔位置是影响 SRF 吸收的重要因素。病程是一个不确定的因素，这是由于几个主观原因。
