免疫纯化的抗苗勒管激素不会抑制大鼠卵母细胞体外减数分裂的自发恢复。
Immunopurified anti-müllerian hormone does not inhibit spontaneous resumption of meiosis in vitro of rat oocytes.
作者信息
Tsafriri A, Picard J Y, Josso N
机构信息
Department of Hormone Research, Weizmann Institute of Science, Rehovot, Israel.
出版信息
Biol Reprod. 1988 Mar;38(2):481-5. doi: 10.1095/biolreprod38.2.481.
The ability of immunopurified, biologically potent anti-Müllerian hormone (AMH) to inhibit the spontaneous resumption of meiosis of rat oocytes was tested in vitro. Two different batches of AMH in the range of 0.75-9.0 micrograms/protein did not suppress the spontaneous resumption of meiosis. Neither did AMH (6 micrograms/ml) induce meiotic resumption of follicle-enclosed oocytes in culture. It is concluded, therefore, that AMH has no oocyte meiosis-inhibiting activity.
在体外测试了免疫纯化的、具有生物活性的抗苗勒管激素（AMH）抑制大鼠卵母细胞减数分裂自发恢复的能力。两批不同的AMH，浓度范围为0.75 - 9.0微克/蛋白质，均未抑制减数分裂的自发恢复。AMH（6微克/毫升）也未诱导培养中卵泡包裹的卵母细胞发生减数分裂恢复。因此得出结论，AMH没有抑制卵母细胞减数分裂的活性。
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