Riashchikov S N, Glumova V A, Markov V N, Bazhenov A N
Biull Eksp Biol Med. 1988 Apr;105(4):507-9.
A considerable decrease in the amount of sympathetic nervous cells in neonatal rats injected guanethidine resulted in the depression of thyroid gland functional activity in 1-month-old animals, there was an apparent parallel increase in the proliferative activity of the gland. A 2/3 thyroidectomy led to the functional tension of the remaining part of the organ. A comparison of compensatory-reparative processes after thyroidectomy has shown similarity of reparative changes in experimental and control rats, however, the degree of repair potential was much higher in the sympathectomized thyroid gland.
给新生大鼠注射胍乙啶后,其交感神经细胞数量显著减少,这导致1月龄动物甲状腺功能活动受到抑制,而甲状腺的增殖活性则明显相应增加。甲状腺切除2/3会导致器官剩余部分出现功能紧张。对甲状腺切除术后的代偿性修复过程进行比较发现,实验大鼠和对照大鼠的修复性变化相似,然而,去交感神经支配的甲状腺的修复潜能程度要高得多。