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[交感神经切除对1月龄大鼠甲状腺代偿性修复过程的影响]

[Characteristics of the compensatory repair processes in the thyroid of 1-month-old rats as affected by sympathectomy].

作者信息

Riashchikov S N, Glumova V A, Markov V N, Bazhenov A N

出版信息

Biull Eksp Biol Med. 1988 Apr;105(4):507-9.

PMID:3359042
Abstract

A considerable decrease in the amount of sympathetic nervous cells in neonatal rats injected guanethidine resulted in the depression of thyroid gland functional activity in 1-month-old animals, there was an apparent parallel increase in the proliferative activity of the gland. A 2/3 thyroidectomy led to the functional tension of the remaining part of the organ. A comparison of compensatory-reparative processes after thyroidectomy has shown similarity of reparative changes in experimental and control rats, however, the degree of repair potential was much higher in the sympathectomized thyroid gland.

摘要

给新生大鼠注射胍乙啶后,其交感神经细胞数量显著减少,这导致1月龄动物甲状腺功能活动受到抑制,而甲状腺的增殖活性则明显相应增加。甲状腺切除2/3会导致器官剩余部分出现功能紧张。对甲状腺切除术后的代偿性修复过程进行比较发现,实验大鼠和对照大鼠的修复性变化相似,然而,去交感神经支配的甲状腺的修复潜能程度要高得多。

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