Lee R M, McKenzie R, Roy M
Department of Anaesthesia, McMaster University, Hamilton, Canada.
Blood Vessels. 1988;25(3):105-14. doi: 10.1159/000158725.
A morphometric and ultrastructural study of superior mesenteric arteries and large mesenteric arteries from newborn spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY) was carried out. Morphometric measurements showed that in both vessel types, cross-sectional areas of the lumen and vessel wall components (e.g., media, adventitia) were similar between SHR and WKY. There was also no ultrastructural difference between SHR and WKY in the two types of arteries. We therefore conclude that vascular alterations found in older SHR take place after birth.
对新生自发性高血压大鼠（SHR）和正常血压的Wistar-Kyoto大鼠（WKY）的肠系膜上动脉和肠系膜大动脉进行了形态计量学和超微结构研究。形态计量学测量表明，在这两种血管类型中，SHR和WKY之间管腔和血管壁成分（如中膜、外膜）的横截面积相似。在这两种动脉类型中，SHR和WKY之间也没有超微结构差异。因此，我们得出结论，在老年SHR中发现的血管改变发生在出生后。
