Division of Dentofacial Anomalies, Department of Maxillofacial Orthopedics and Orthodontics, Wroclaw Medical University, Poland.
Dent Med Probl. 2021 Jan-Mar;58(1):123-126. doi: 10.17219/dmp/131989.
The infection with a new type of virus - severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - called coronavirus disease 2019 (COVID-19) was first described in December 2019, in Wuhan, China. Due to the gastrointestinal mucosa tropism of the virus, an attempt was made to describe the oral manifestations of the SARS-CoV-2 infection. Angiotensin-converting enzyme 2 (ACE2), which permits the attachment of the virus, is present also in the oral cavity. There are many symptoms in the oral cavity; among them, the most prevalent ones are dysgeusia (taste disorders), oral pain, the exacerbation of autoimmune diseases as well as the herpes simplex virus (HSV) and varicella zoster virus (VZV) infections. Ulcerations and aphthous stomatitis are also often mentioned. The research shows that there are many oral symptoms in COVID-19, but the coexistence with the main disease has not been fully stated and understood. There is still no clearance on whether the oral symptoms are the manifestations of the disease or occur due to the loss of the immune response. Therefore, further studies on this subject should be conducted.
新型病毒——严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)引起的感染,于 2019 年 12 月在中国武汉首次被描述为 2019 年冠状病毒病(COVID-19)。由于病毒对胃肠道黏膜的亲嗜性,人们试图描述 SARS-CoV-2 感染的口腔表现。血管紧张素转换酶 2(ACE2)允许病毒附着,也存在于口腔中。口腔中有许多症状;其中,最常见的是味觉障碍(味觉障碍)、口腔疼痛、自身免疫性疾病的恶化以及单纯疱疹病毒(HSV)和水痘带状疱疹病毒(VZV)感染。溃疡和口疮性口炎也经常被提及。研究表明,COVID-19 有许多口腔症状,但与主要疾病的共存尚未得到充分说明和理解。目前仍不清楚口腔症状是疾病的表现还是由于免疫反应丧失而发生的。因此,应该对这一主题进行进一步的研究。
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