Convexity preserving level set for left ventricle segmentation.

In clinical applications of cardiac left ventricle (LV) segmentation, the segmented LV is desired to include the cavity, trabeculae, and papillary muscles, which form a convex shape. However, the intensities of trabeculae and papillary muscles are similar to myocardium. Consequently, segmentation algorithms may easily misclassify trabeculae and papillary muscles as myocardium. In this paper, we propose a level set method with a convexity preserving mechanism to ensure the convexity of the segmented LV. In the proposed level set method, the curvature of the level set contours is used to control their convexity, such that the level set contour is finally deformed as a convex shape. The experimental results and the comparison with other level set methods show the advantage of our method in terms of segmentation accuracy. Compared with the state-of-the-art methods using deep-learning, our method is able to achieve comparable segmentation accuracy without the need for training, while the deep-learning based method requires a large set of training data and high-quality manual segmentation. Therefore, our method can be conveniently used in situation where training data and their manual segmentation are not available.