Dipartimento di Fisica e Chimica, Università degli Studi di Palermo, Viale delle Scienze pad 17, 90128 Palermo, Italy; Institut Max von Laue - Paul Langevin, 71 avenue des Martyrs, 38042 Grenoble, France.
Dipartimento di Fisica e Chimica, Università degli Studi di Palermo, Viale delle Scienze pad 17, 90128 Palermo, Italy.
Adv Colloid Interface Sci. 2021 Mar;289:102375. doi: 10.1016/j.cis.2021.102375. Epub 2021 Feb 5.
Cyclodextrins (CDs) play an important role in self-assembly systems of amphiphiles. The structure of CDs provides distinguished physicochemical properties, including the ability to form host-guest complexes. The complexation affects the properties of guest molecules and can produce supramolecular aggregates with desirable characteristics for fundamental and practical applications. Surfactants are particularly attractive host molecules due to their wide variety, availability, responsiveness to different stimuli, and high relevance in different fields, e.g. medical, cosmetic, pharmaceutical, and food industries. The tendency of organization in higher-order supramolecular aggregates arises the interest in applying such versatile complexes in the development of novel materials. In this review, we provide a comprehensive overview of the thermodynamics aspects of surfactants and CDs inclusion complexes formation in aqueous environment, emphasizing the assessment of the interactions, thermodynamic driving forces, and structural aspects. Also, the most common analytical techniques used to gather deep insight into the aspects of CDs complexes are discussed and the perspectives for the surfactant-cyclodextrin complexes are pointed out.
环糊精 (CDs) 在两亲分子的自组装体系中起着重要作用。CDs 的结构提供了独特的物理化学性质，包括形成主客体配合物的能力。这种配合作用影响客体分子的性质，并能产生具有理想特性的超分子聚集体，可应用于基础和实际应用。由于其种类繁多、可用性高、对不同刺激的响应性以及在医学、化妆品、制药和食品等不同领域的高度相关性，表面活性剂是特别有吸引力的主体分子。在更高阶超分子聚集体中组织的趋势引起了人们对应用这种多功能配合物开发新型材料的兴趣。在这篇综述中，我们全面概述了表面活性剂和 CDs 在水相环境中形成包合物的热力学方面，强调了对相互作用、热力学驱动力和结构方面的评估。此外，还讨论了用于深入了解 CDs 配合物各方面的最常见分析技术，并指出了表面活性剂-环糊精配合物的前景。
