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基于在中国东北锌冶炼区不同暴露时间的灰尘,街头清洁工暴露于镉、铅和砷的情况。

Exposure of street sweepers to cadmium, lead, and arsenic in dust based on variable exposure duration in zinc smelting district, Northeast China.

机构信息

Key Laboratory of Groundwater Resources and Environment of the Ministry of Education, College of New Energy and Environment, Jilin University, China.

Department of Dermatology, First Hospital of Jilin University, Changchun, Jilin, China.

出版信息

Chemosphere. 2021 Jun;272:129850. doi: 10.1016/j.chemosphere.2021.129850. Epub 2021 Feb 4.

Abstract

Street dust is an important contributor to heavy metal exposure in street sweepers. In this work, the levels of cadmium (Cd), lead (Pb), and arsenic (As) in street dust were evaluated, and the corresponding health implications for street sweepers in the smelting district of Huludao city northeast China were assessed. The contributions of dietary sources and dust to total metal exposure in street sweepers were compared. Because street sweepers are exposed to street dust both during work and nonwork hours, the health risks faced by street sweepers are uncertain. Therefore, variable exposure duration was considered using a deterministic model. A probabilistic risk assessment model was developed to explore the health effects of street dust on street sweepers via Monte Carlo simulation. The various exposure parameters that affect risk were analyzed using sensitivity analysis. The average Cd, Pb, and As levels in the hair of street sweepers were 2.04, 20.12, and 0.52 mg·kg, respectively. These values were higher than those for residents (i.e., not street sweepers) of Huludao. Strong correlations were found between the logarithms (base 10) of the Cd, Pb, and As contents in dust and hair (r = 0.581, p < 0.01; r = 0.428, p < 0.01; r = 0.378, p < 0.01; n = 62). Based on analysis using deterministic models, the maximum exposures to Cd and Pb via dust through the alimentary canal were nearly three and six times higher than the dietary exposures, respectively. Sensitivity analysis indicated that exposure duration is an important parameter.

摘要

街道灰尘是街头清洁工重金属暴露的一个重要来源。在这项工作中,评估了街道灰尘中镉 (Cd)、铅 (Pb) 和砷 (As) 的水平,并评估了中国东北部葫芦岛冶炼区街头清洁工的相应健康影响。比较了饮食来源和灰尘对街头清洁工体内金属总暴露量的贡献。由于街头清洁工在工作和非工作时间都接触街道灰尘,因此他们面临的健康风险是不确定的。因此,使用确定性模型考虑了可变暴露时间。开发了一个概率风险评估模型,通过蒙特卡罗模拟来探索街道灰尘对街头清洁工的健康影响。使用敏感性分析分析了影响风险的各种暴露参数。街头清洁工头发中的平均 Cd、Pb 和 As 含量分别为 2.04、20.12 和 0.52mg·kg。这些值高于葫芦岛居民(即非街头清洁工)的值。发现灰尘和头发中 Cd、Pb 和 As 含量的对数(以 10 为底)之间存在很强的相关性(r = 0.581,p < 0.01;r = 0.428,p < 0.01;r = 0.378,p < 0.01;n = 62)。基于确定性模型的分析,通过消化道从灰尘中摄入 Cd 和 Pb 的最大暴露量分别接近饮食暴露量的三倍和六倍。敏感性分析表明,暴露时间是一个重要参数。

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