Mendoza-Lagunas José Leopoldo, Aguilar-Espinosa Alejandra Damayanti, Rodríguez-Cantú Laura Nelly, Guerra-González Roberto, Meza-Figueroa Diana María, Meza-Montenegro María Mercedes, Martínez-Cinco Marco A
Dirección Adjunta de Investigación Humanidades y Ciencia, Consejo Nacional de Humanidades Ciencia y Tecnología, Benito Juarez, CIudad de México, Mexico.
Facultad de Ingeniería Química, Universidad Michoacana de San Nicolás de Hidalgo, Morelia, Michoacán, Mexico.
PeerJ. 2025 Jun 10;13:e18805. doi: 10.7717/peerj.18805. eCollection 2025.
Arsenic (As) is a globally distributed metalloid that is emitted from natural sources, including geothermal processes, as well as from anthropogenic activities. The village of Araró, in the state of Michoacán, is located in the Trans-Mexico volcanic belt, which is a highly active geothermal site in central Mexico. The aim of this study is to evaluate the health risk to residents of the town from As exposure from dust through oral, dermal and inhalation pathways, using Monte Carlo simulation. Forty dust samples were randomly collected in Araró village, and these were analyzed using portable X-ray fluoroscopy. The As levels obtained for dust samples ranged from 5.94 to 42.53 mg/kg. Point estimation of hazard quotient (HQ) and its probability distribution was assessed using U.S. Environmental Protection Agency (USEPA) formulas and Monte Carlo simulation, respectively, for oral, dermal and inhalation pathways. Anthropometrical data were obtained from the Health and Nutrition National Survey 2018. Mean average daily dose (ADD) for all age groups (preschooler, Elementary (6-12), adolescent and adult) were below safety limits. A total of 4 and 6% of preschooler and Elementary dermal ADDs were above safety limits. For oral and dermal exposure in children, HQ and hazard index (HI) mean values were higher than other age groups, despite safety limits not being reached. Also, it was found that dermal carcinogenic risk (CR) value for adults may represent a potential cancer risk. Despite a relatively low reported concentration of As it is important that more As exposure routes be explored to determine the severity of the problem because previous studies have shown high As concentrations in drinking water.
砷(As)是一种全球分布的类金属,它来自包括地热过程在内的自然源以及人为活动。米却肯州的阿拉罗村位于墨西哥火山带,这是墨西哥中部一个高度活跃的地热区。本研究的目的是使用蒙特卡洛模拟评估该镇居民通过口服、皮肤和吸入途径接触粉尘中的砷所面临的健康风险。在阿拉罗村随机采集了40个粉尘样本,并使用便携式X射线荧光光谱仪进行分析。粉尘样本中的砷含量范围为5.94至42.53毫克/千克。分别使用美国环境保护局(USEPA)公式和蒙特卡洛模拟评估口服、皮肤和吸入途径的危害商(HQ)点估计及其概率分布。人体测量数据取自2018年全国健康与营养调查。所有年龄组(学龄前儿童、小学生(6 - 12岁)、青少年和成年人)的平均每日剂量(ADD)均低于安全限值。学龄前儿童和小学生的皮肤ADD分别有4%和6%高于安全限值。对于儿童的口服和皮肤接触,尽管未达到安全限值,但HQ和危害指数(HI)的平均值高于其他年龄组。此外,还发现成年人的皮肤致癌风险(CR)值可能代表潜在的癌症风险。尽管报告的砷浓度相对较低,但由于先前的研究表明饮用水中的砷浓度较高,因此探索更多的砷接触途径以确定问题的严重性很重要。