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孕期规律运动对超重和肥胖孕妇的长期影响:一项随机对照试验方案。

Long-term effects of regular exercise during pregnancy on overweight and obese gravidas: A protocol of randomized controlled trial.

机构信息

Department of Obstetrics, Wuhan Central Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiangan District, Wuhan City, Hubei Province, P.R. China.

出版信息

Medicine (Baltimore). 2021 Feb 5;100(5):e23955. doi: 10.1097/MD.0000000000023955.

Abstract

BACKGROUND

Overweight before pregnancy is independent risk factor for diabetes mellitus. This randomized controlled trial was to investigate the long-term effects of regular exercise during pregnancy on overweight and obese gravidas.

METHODS AND ANALYSIS

This single-center, prospective, randomized controlled test will be conducted in Wuhan Central Hospital, Tongji Medical College, Huazhong University of Science and Technology. Overweight and obese pregnant women will be included in our study and randomized into 2 groups: regular exercise and control groups. The informed consent will be acquired in each patient. Body weight, body fat, fasting and 2 h glucose level in 75 g oral glucose tolerance test (OGTT), insulin resistance index, and lipid profiles were compared. We also evaluated their physical activities with International Physical Activity Questionnaire (IPAQ), their dietary habits with modified Adult Dietary Behavior Assessment Scale, and depression condition with Postpartum Depression Screen Scale (PDSS). The significance level was defaulted as P < .05.

RESULTS

Results will be published in relevant peer-reviewed journals.

CONCLUSION

Our study aims to systematically assess the effects of regular exercise for overweight and obese gravidas, which will be provided clinical guidance for overweight and obese gravidas.

摘要

背景

妊娠前超重是糖尿病的独立危险因素。本随机对照试验旨在研究孕期规律运动对超重和肥胖孕妇的长期影响。

方法和分析

本单中心、前瞻性、随机对照试验将在华中科技大学同济医学院武汉中心医院进行。超重和肥胖孕妇将被纳入我们的研究,并随机分为两组:规律运动组和对照组。每位患者都将获得知情同意。比较体重、体脂、75g 口服葡萄糖耐量试验(OGTT)空腹和 2 小时血糖水平、胰岛素抵抗指数和血脂谱。我们还使用国际体力活动问卷(IPAQ)评估了她们的体力活动、改良成人饮食行为评估量表(modified Adult Dietary Behavior Assessment Scale)评估了她们的饮食习惯以及产后抑郁筛查量表(Postpartum Depression Screen Scale,PDSS)评估了她们的抑郁状况。默认显著性水平为 P<0.05。

结果

研究结果将发表在相关同行评议期刊上。

结论

本研究旨在系统评估规律运动对超重和肥胖孕妇的影响,为超重和肥胖孕妇提供临床指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4cb/7870188/63198440aef5/medi-100-e23955-g001.jpg

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